Dexamethasone Levels Predict Cortisol Response after Infant Cardiopulmonary Bypass
We hypothesized that postoperative dexamethasone drug levels are highly variable, and that the infant stress response is related inversely to the amount of dexamethasone measured in the blood.
The Efficacy of Caudal Dexmedetomidine on Stress Response and Postoperative Pain in Pediatric Cardiac Surgery
We studied efficacy of caudal dexmedetomidine (DEX) on attenuation of perioperative stress response and postoperative pain in pediatric patients undergoing cardiac surgery.
Effect of Pre-Bypass Methylprednisolone on Post-Operative Renal Function Following Correction of Atrial Septal Defect Under Cardiopulmonary Bypass
The purpose of this study was to compare the effects of pre-bypass and post-bypass methylprednisolone on postoperative renal function after correction of ASD under CPB.
The Inflammatory Response to Cardiac Surgery with Cardiopulmonary Bypass: Should Steroid Prophylaxis be Routine
In adult cardiac surgery with CPB, steroids have been rigorously evaluated in multiple randomized clinical trials and meta-analyses.
Blood Conservation Strategies in Cardiac Surgery: More is Better
Recent data show that up to 50% of heart procedures require blood transfusion, which can have adverse long- and short-term outcomes for the patient. This led to the updated 2011 Society of Thoracic Surgery (STS)/Society of Cardiovascular Anesthesiologists (SCA) guidelines in an attempt to adopt more effective blood conservation techniques.
Indications for Cardiopulmonary Bypass During Pregnancy and Impact on Fetal Outcomes
Cardiac operations in pregnant patients are a challenge for physicians in multidisciplinary teams due to the complexity of the condition which affects both mother and baby.
Impaired Red Blood Cell Deformability after Transfusion of Stored Allogeneic Blood but not Autologous Salvaged Blood in Cardiac Surgery Patients
We tested the hypothesis that in cardiac surgery patients, RBC deformability and aggregation are minimally affected by CPB with autologous salvaged blood alone but are negatively affected by the addition of stored allogeneic blood.
The “Benefits” of the Mini-Extracorporeal Circulation in the Minimal Invasive Cardiac Surgery Era
Mini-extracorporeal circulation (MECC) constitutes a novel miniaturized cardiopulmonary bypass (CPB) circuit, heparin-coated and primed with aprotinin.
Stem Cell Therapy for Chronic Ischaemic Heart Disease and Congestive Heart Failure
A promising approach to the treatment of chronic ischaemic heart disease (IHD) and heart failure is the use of stem cells.
Hyperkalemic Cardioplegia for Adult and Pediatric Surgery: End of an Era?
This review provides a brief history of high K(+) cardioplegia, five areas of increasing concern with prolonged membrane K(+) depolarization, and the basic science and clinical data underpinning a new normokalemic, "polarizing" cardioplegia comprising adenosine and lidocaine (AL) with magnesium (Mg(2+)) (ALM™).