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Tranexamic Acid Attenuates Inflammatory Response in Cardiopulmonary Bypass Surgery Through Blockade of Fibrinolysis: A Case Control Study Followed by a Randomized Double-Blind Controlled Trial
Tranexamic acid (TA) reduces fibrinolysis and blood loss after cardiopulmonary bypass (CPB). However, its effects on IR and vasoplegic shock (VS) are not well known and this was the main objective of this study.
An Evaluation of the Benefits of Pulsatile versus Nonpulsatile Perfusion during Cardiopulmonary Bypass Procedures in Pediatric and Adult Cardiac Patients
The objective of this investigation was to review the literature in order to clarify the truths and dispel the myths regarding the mode of perfusion used during open-heart surgery in pediatric and adult patients.
The Efficacy and Safety of Prophylactic Corticosteroids for the Prevention of Adverse Outcomes in Patients Undergoing Heart Surgery Using Cardiopulmonary Bypass: a Systematic Review and Meta-Analysis of Randomized Controlled Trials
In the present meta-analysis of 62 RCTs (16 457 patients), including the 2 major RCTs (SIRS and DECS trials: 12 001 patients), we found that prophylactic corticosteroids in cardiac surgery did not reduce mortality.