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Mini-Extracorporeal Circulation Minimizes Coagulation Abnormalities and Ameliorates Pulmonary Outcome in Coronary Artery Bypass Grafting Surgery
Hemostasis is impaired during CABG and coagulation abnormalities often result in clinically relevant organ dysfunctions, eventually increasing morbidity and mortality rates.
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Inhaled Nitric Oxide Reduces Injury and Microglia Activation in Porcine Hippocampus after Deep Hypothermic Circulatory Arrest
Using DHCA for 30 minutes, consistent with clinical exposure, we noted that iNO reduces neuronal degeneration in the hippocampus. In addition, iNO reduces microglial activation in the hippocampus after DHCA. The data suggest that iNO reduces neuronal degeneration by ameliorating inflammation and may be a practical mode of neuroprotection for infants undergoing DHCA.
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