Systematic Review from the ICEBP Perfusion Guidelines Committee on Anti-Inflammatory Agents Plus a Meta-Analysis on the Anti-Inflammatory Effects of Aprotinin (Video)
World's Largest Resource for Cardiovascular Perfusion
Extracorporeal membrane oxygenation (ECMO) is increasingly used to save patients with severe cardiopulmonary failure at high risk of dying, but the long-term psychiatric outcome of the treatment has not been studied.
Although isoflurane preconditioning resulted in a reduction in infarct size at all concentrations used, the protection was mediated by phosphorylation and translocation of PKC only at 0.4 MAC.
MSC delivery through CPB has the potential to mitigate effects of CPB on neural stem/progenitor cells and to promote migration of neuroblasts. Further investigation is necessary to determine the long-term effect of MSC treatment during CPB on postnatal neurogenesis.