We briefly discuss the evidence for cardiopulmonary bypass-related neuronal injuries in adult cardiac surgery patients, and review the evidence that immune priming is a key factor in the pathogenesis of cognitive dysfunction after cardiac surgery.
Common reasons for replacing the ECMO circuit include the buildup of blood clots, with or without an increase in Delta P. This condition can be linked to the activation of the coagulation process and inflammation, such as a rise in D-Dimer levels and a decrease in fibrinogen levels (less than 2).