Retrograde Autologous Priming to Reduce Allogeneic Blood Transfusion Requirements: a Systematic Review
Prospective, randomized multi-center trials are warranted to conclude decisively on the benefits of retrograde autologous priming.
World's Largest Resource for Cardiovascular Perfusion
Prospective, randomized multi-center trials are warranted to conclude decisively on the benefits of retrograde autologous priming.
With careful evaluation and monitoring in addition to appropriate intervention, a uniformly good outcome may be possible even for these most complicated patients.
Congenital heart disease (CHD) is a major cause of infant mortality. Many infants with CHD require corrective surgery with most operations requiring cardiopulmonary bypass (CPB). CPB triggers a systemic inflammatory response which is associated with low cardiac output syndrome (LCOS), postoperative morbidity and mortality. Delivery of nitric oxide (NO) into CPB circuits can provide myocardial protection and reduce bypass-induced inflammation, leading to less LCOS and improved recovery.