Heparin Alternatives

A Randomized, Double Blind Trial of Prophylactic Fibrinogen to Reduce Bleeding in Cardiac Surgery

Postoperative bleeding has a great clinical importance and can contribute to increased mortality and morbidity in patients undergoing coronary artery bypass graft surgery. In this prospective, randomized, double-blind study, we evaluated the effect of prophylactic administration of fibrinogen concentrate on post-coronary artery bypass graft surgery bleeding.