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A Single Preoperative Dose of Tranexamic Acid Reduces Perioperative Blood Loss
Preoperative intravenous TXA reduced perioperative blood loss and transfusion requirements in a variety of surgical disciplines without increasing the risk of thromboembolic events. Therefore, it should be considered for prophylactic use in surgery to reduce operative bleeding.
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Improved Creatinine-Based Early Detection of Acute Kidney Injury after Cardiac Surgery
Model DynaLab’ improves early detection of CSA-AKI within 12 h after surgery. This simple Cr-based framework poses a fundament for further endeavours towards reduction of CSA-AKI incidence and severity.
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Aprotinin Inhibits Proinflammatory Activation of Endothelial Cells by Thrombin Through the Protease-Activated Receptor 1
Here we have examined whether aprotinin inhibits endothelial protease-activated receptor 1 activation and resulting proinflammatory responses induced by thrombin.
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