The Effect of Adult and Pediatric Cardiopulmonary Bypass on Pharmacokinetic and Pharmacodynamic Parameters
Cardiopulmonary bypass (CPB) is known to have important effects on the disposition of drugs,
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The Current Place of Aprotinin in the Management of Bleeding
Following its withdrawal in 2007, which is explained in detail in this review, the regulators have now licensed aprotinin for myocardial revascularisation only, which is relatively low-risk for bleeding.
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