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The Nondepolarizing, Normokalemic Cardioplegia Formulation Adenosine-Lidocaine (Adenocaine) Exerts Anti-Neutrophil Effects by Synergistic Actions of its Components
Adenocaine suppresses multiple PMN functions including O(2)(-) generation, adhesion molecule expression, PMN adherence, and transmigration. In addition to inducing nondepolarized arrest, adenocaine cardioplegia may exert cardioprotection by inhibiting PMN-mediated inflammatory responses.
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Acute Kidney Injury after Cardiac Surgery: Does the Time Interval from Contrast Administration to Surgery Matter?
The authors sought to evaluate the association between the time interval from contrast administration to cardiac surgery and postoperative acute kidney injury (AKI).
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Intermittent Urine Oxygen Tension Monitoring for Predicting Acute Kidney Injury After Cardiovascular Surgery: A Preliminary Prospective Observational Study
Intermittent PuO2 values at six and 12 hours after ICU admission may be predictors of AKI, although the AUCs to predict AKI were low (0.68 and 0.64). AKI prediction by PuO2 was not possible immediately after induction of general anesthesia (not statistically significant) and immediately after ICU admission (AUC was very low). Further studies are required to confirm the validity of intermittent PuO2 monitoring.
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