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Clinical Monitoring of Activated Clotting Time during Cardiothoracic Surgery: Comparing the Hemochron® Response and Hemochron® Signature Elite
The Elite was more reliable, but the variation was higher for the Elite than the Response. The observed positive bias in the Response compared to the Elite could affect heparin administration during surgery making the two systems not interchangeable.
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Urinary TIMP-2 and IGFBP7 for the Prediction of Acute Kidney Injury Following Cardiac Surgery
Acute kidney injury (AKI) following cardiac surgery is common and associated with poor patient outcomes. Early risk assessment for development of AKI remains a challenge. The combination of urinary tissue inhibitor of metalloproteinase 2 (TIMP-2) and insulin-like growth factor binding protein 7 (IGFBP7) has been shown to be an excellent predictor of AKI following cardiac surgery.
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