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A Multicenter Pilot Study Assessing Regional Cerebral Oxygen Desaturation Frequency During Cardiopulmonary Bypass and Responsiveness to an Intervention Algorithm

The purpose of this multicenter pilot study was to: (1) determine the frequency of regional cerebral oxygen saturation (rScO2) desaturations during cardiac surgery involving cardiopulmonary bypass (CPB); (2) evaluate the accuracy of clinician-identified rScO2 desaturations compared with those recorded continuously during surgery by the near-infrared spectroscopy (NIRS) monitor; and (3) assess the effectiveness of an intervention algorithm for reversing rScO2 desaturations.

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Main Zone, Mobile Zone, Perfusion Zone

Off-Pump Coronary Artery Bypass Graft Surgery is Standard of Care: Where Do You Stand?

several large, nonrandomized retrospective case series. The studies demonstrated that CABG can be performed safely without CPB (off-pump surgery), and suggested that there are benefits compared with conventional CABG. However, the randomized controlled studies published to date have been, as a whole, unable to conclusively demonstrate advantages of off-pump CABG.

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