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Risk Assessment of Acute Kidney Injury Following Cardiopulmonary Bypass
Evaluation of patients by the RIFLE versus SOP criteria yielded different results with more AKI patients detected by SOP. Based on the present data, it is concluded that patients may not prone to AKI when surgery and ischemia time will be kept short, when blood loss is mitigated to a minimum and when surgery is performed under non-hypothermic conditions.
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Extracts of Adipose Derived Stem Cells Slows Progression in the R6/2 Model of Huntington’s Disease
Stem cell transplantation has been investigated as a therapeutic strategy to treat the Huntington's disease (HD). Considering clinical feasibility and safety, injection of cell-free extracts of ASCs (ASCs-E) could be effective and safe strategy for HD patients, comparable to the stem cell therapy. Findings from our study provide possible strategy to inhibit HD progression and reasonable resources for treatment.
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A Pilot Randomized Controlled Study of Mild Hypercapnia During Cardiac Surgery With Cardiopulmonary Bypass
To test whether targeted therapeutic mild hypercapnia (TTMH) would attenuate cerebral oxygen desaturation detected using near-infrared spectroscopy during cardiac surgery requiring cardiopulmonary bypass (CPB).
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