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Aprotinin Improves Cerebral Protection: Evidence From a Survival Porcine Model
The goal of the study was to test the hypothesis that aprotinin could reduce cerebral injury after low-flow cardiopulmonary bypass and deep hypothermic circulatory arrest.
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Percutaneous Closure of a Patent Foramen Ovale to Prevent Paradoxical Thromboembolism in a Patient With a Continuous-Flow LVAD
Strategies to diagnose PFO at the time of LVAD implantation and physiological implications of a right-to-left atrial shunt during mechanical unloading of the failing left ventricle are reviewed.
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Protamine Test Dose: Impact on Activated Clotting Time and Circuit Integrity
Regardless of the protamine test dosage, there is no reliable way to predict how a patient’s ACT will respond to a protamine test dose. Clot formation and circuit integrity is at risk when pump suction devices are continuously in use during PTD administration. Therefore, we strongly recommend that the direct recovery of mediastinal shed blood into the pump circuit be discontinued before any amount of protamine is administered to the patient.
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