Cloned Knockout Mini-pigs Hold Potential for Organ Xenotransplantation
By deleting the immunogenic alpha-1,3-galactosyltransferase (GGTA1) gene in cloned miniature swine, researchers in the US and Korea appear to have moved closer […]
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The Risk Associated with Aprotinin in Cardiac Surgery
In this observational study involving 4374 patients undergoing revascularization, we prospectively assessed three agents (aprotinin [1295 patients], aminocaproic acid [883], and tranexamic acid [822]) as compared with no agent (1374 patients) with regard to serious outcomes by propensity and multivariable methods.
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Left Ventricular Unloading is Associated with Lower Mortality in Cardiogenic Shock Patients Treated with Veno-Arterial Extracorporeal Membrane Oxygenation: Results From An International, Multicenter Cohort Study
These findings support use of left ventricular unloading in cardiogenic shock patients treated with VA-ECMO and call for further validation, ideally in a randomized, controlled trial.
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