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Diabetics With Autonomic Neuropathy Have Decreased Myocardial Perfusion Reserve
Type 1 diabetics with autonomic neuropathy exhibit decreased myocardial perfusion reserve capacity when challenged with a vasodilator. This finding may be related […]
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Toll-like Receptor 9 and the Inflammatory Response to Surgical Trauma and Cardiopulmonary Bypass
CPB, surgical trauma and ischemic perfusion injury trigger the release of circulating mtDNA that activates TLR-9, in turn stimulating a release of IL-6. Therefore, TLR-9 antagonists may attenuate this response and may provide a future therapeutic target whereby the systemic inflammatory response to cardiac surgery may be manipulated to improve clinical outcomes.
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Terumo Signs Consent Decree with the FDA (Press Release)
During an inspection last year at Terumo Cardiovascular Systems Ann Arbor, Mich., plant, FDA officials found numerous violations to good manufacturing practice and medical device reporting requirements. On March 17, Terumo executive officers signed a consent decree of permanent injunction and under its terms, Terumo will pay almost $35 million in profits from past sales to the federal government.
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