Prevention of this disastrous complication appears to be better than treatment once it is fully established. However newer aggressive forms of early renal replacement/transplant therapies may have some promise.
Supra-physiologic HCT causes abnormal ROTEM test results consistent with increased dilution of fibrinogen and coagulation factors in whole blood by red cells.
We set up a study to explore the presence of coronary baroreceptors in humans, which was performed with isolated, graded aortic root perfusion in patients during cardiopulmonary bypass.