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Mechanical Circulatory Support for Heart Failure: Past, Present and a Look at the Future
This review provides a perspective on the past, present and future of mechanical circulatory support and addresses the changes in technology, patient selection and management strategies needed to have this therapy fully embraced by the heart failure community, and perhaps replace heart transplantation either as the therapy of choice or as a strategy by which to delay transplantation in younger patients.
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Deep Hypothermic Circulatory Arrest Activates Neural Precursor Cells in Neonatal Brain
Neonatal piglet ACP at 18°C or 25°C provides adequate protection from increased brain cellular apoptosis. In contrast to ACP however, DHCA induces brain Nestin expression, indicating activation of neural progenitor cells and the potential of altering neonatal neurodevelopmental progression.
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