Clinical Evaluation of Air Handling in Pediatric Cardiac Surgery: Do We Really Need Arterial Filter in Neonatal and Infant Surgery? (EP Video)

The impairment of microvascular endothelial function during CPB in cardiac surgery for the correction of congenital heart defects appears to be related to a reduced systemic bioavailability of NO, resulting from the inflammatory and pro-oxidative response typical of this surgical procedure.