Cardiac Disease in Offspring Linked to Maternal Malnutrition in Early Gestation
The first evidence to link maternal malnutrition during early gestation with the development of coronary heart disease in offspring is reported by […]
Clinical Experience With the Mini-Extracorporeal Circulation System: An Evolution or a Revolution
PURPOSE: We studied a cohort of 150 patients operated on with a new cardiopulmonary bypass (CPB) system. This is the mini-extracorporeal circulation […]
Myocyte Contractility With Caspase Inhibition and Simulated Hyperkalemic Cardioplegic Arrest
BACKGROUND: Exposure of left ventricular (LV) myocytes to simulated hyperkalemic cardioplegic arrest (HCA) has been demonstrated to perturb ionic homeostasis and adversely […]
Graft Patency Rates Lower With Off-Pump CABG
In a prospective randomized study, patients who underwent coronary artery bypass surgery (CABG) without cardiopulmonary bypass and cardiac arrest (off-pump CABG) had […]
Off-Pump CABG as Effective as Conventional Bypass Surgery, But Less Costly
Off-pump CABG is comparable to conventional bypass surgery in terms of early and 1-year graft patency and quality-of-life outcomes, according to a […]
Influence of Two Different Perfusion Systems on Inflammatory Response in Pediatric Heart Surgery
Background: This study tests the hypothesis that a cardiopulmonary bypass system that combines complete heparin-coating, a centrifugal pump, and a closed circuit […]
High Prevalence of Platelet Function Abnormalities in Patients with Aortic Stenosis
Platelet function abnormalities and acquired von Willebrand syndrome is found in more than 20% of patients with aortic stenosis. The abnormalities tend […]
Percutaneous Coronary Intervention Superior in Some Post–Coronary Bypass Graft Patients
Percutaneous coronary intervention (PCI) may be preferable to repeat coronary artery bypass graft (CABG) for many CABG patients. This is the conclusion […]
The Rewarming Rate and Increased Peak Temperature Alter Neurocognitive Outcome After Cardiac Surgery
Neurocognitive dysfunction is a common complication after cardiac surgery. We evaluated in this prospective study the effect of rewarming rate on neurocognitive […]
Silent Ischaemia And Hypertension Continue To Perplex Cardiologists
Treatment of silent ischaemia and angina pectoris is largely the same but it remains unclear whether all ischaemic episodes or only symptomatic […]
Local Gene Transfer of phVEGF-2 Plasmid by Gene-Eluting Stents
Background: Drug-eluting stents represent a useful strategy for the prevention of restenosis using various antiproliferative drugs. These strategies share the liability of […]
Symmetry Bypass Connector Device Linked to Recalcitrant Neointimal Hyperplasia
The recently introduced Symmetry Bypass Connector device seems to be associated with a high rate of acute coronary syndromes within 6 months […]