Angiogenesis: Protein, Gene, or Cell Therapy?
The purpose of this review is to highlight the current progress, controversies, and challenges in the development of protein, gene, and cell-based approaches for clinical therapeutic angiogenesis.
Autologous Blood Transfusion in Total Hip Arthroplasty
Combined use of the preoperative blood pooling and intra-operative recovery systems is effective for avoiding homologous blood transfusion.
Intraoperative Cell Salvage During Radical Prostatectomy: A Safe Technique for Jehovah’s Witnesses
Radical retropubic prostatectomy (RRP) is an operation historically associated with the potential for significant blood loss. Patients who refuse a blood transfusion, such as Jehovah’s witnesses, may be only offered radiation therapy as potentially curative treatment for prostate cancer because of the potential for a transfusion.
Postoperative Antithrombin Levels and Outcome in Cardiac Operations
Low levels of ICU-antithrombin activity are associated with a poor outcome in cardiac surgery; ICU-antithrombin activity is predictive of prolonged ICU stay.
Psychiatric and Psychosocial Outcome of Cardiac Surgery With Cardiopulmonary Bypass: A Prospective 12-Month Follow-up Study
Little is known concerning the natural history of psychiatric morbidity, postoperative delirium, cognitive decline and health-related quality of life (HRQOL) in cardiac surgery patients and the impact of neurocognitive dysfunction on HRQOL after cardiac surgery with cardiopulmonary bypass (CPB).
Immunoglobulin Levels and Lymphocyte Subsets Following Cardiac Operations: Further Evidence for a T-Helper Cell Shifting
Therefore, the objectives of this study were 1) to elucidate the effects of CPB on perioperative immunoglobulin levels, and 2) to find out if alterations in lymphocyte subsets are related to these findings.
Comparison of Platelet Aggregation and Adenosine Triphosphate Secretion in Whole Blood and Platelet-Rich Plasma From Normal Dogs
Platelet aggregation and adenosine triphosphate (ATP) secretion were measured in whole blood and platelet-rich plasma (PRP) from normal dogs using electrical impedance and turbidimetric techniques.
The Risk of Stroke Following CABG: One Possible Strategy to Reduce it?
Stroke remains a devastating complication of coronary artery bypass grafting (CABG): we evaluated whether a more aggressive diagnostic and therapeutic approach can reduce its incidence.
Neural Protection And CPB: Staying On The Cutting Edge
This CME-accredited activity has been designed to meet the educational needs of physicians involved in the management of patients undergoing heart surgery. […]
A Phase III, Double-blind, Placebo-controlled, Multicenter Study on the Efficacy of Recombinant Human Antithrombin in Heparin-resistant Patients Scheduled to Undergo Cardiac Surgery Necessitating Cardiopulmonary Bypass
Treatment with 75 U/kg rhAT is effective in restoring heparin responsiveness and promoting therapeutic anticoagulation in the majority of heparin-resistant patients. Treating heparin-resistant patients with rhAT may decrease the requirement for heparin and fresh frozen plasma.
Body Mass Index and Outcomes After Left Ventricular Assist Device Placement
Higher BMI did not adversely affect survival after LVAD implantation and therefore relative obesity should not be considered a contraindication for LVAD placement.
Improvement of Myocardial Stress Perfusion After Off-Pump Revascularization Using Bilateral Internal Thoracic In Situ Grafts Versus Y-Composite Grafts
Myocardial SPECT demonstrated that revascularization using bilateral in situ ITAs exhibited a greater level of improvement with regard to stress perfusion postoperatively compared with Y-composite grafts.