Impact of Experimental Haemodilution on Platelet Function, Thrombin Generation and Clot Firmness: Effects of Different Coagulation Factor Concentrates
The haemostatic alterations caused by haemodilution are multifactorial and affect both blood cells and coagulation.
In Vitro Comparison of Two Different Methods of Cell Washing
The objective of this study was to compare the product created by washing a unit of RBCs with the AutoLog autotransfusion device in the operating room to the washed products from a standard cell washer in the blood bank.
Comparison of Modified Chandler, Roller Pump, and Ball Valve Circulation Models for in vitro Testing in High Blood Flow Conditions: Application in Thrombogenicity Testing of Different Materials for Vascular Applications
Three different models, a modified Chandler loop, roller pump, and a new ball valve model (Hemobile), were compared with regard to intrinsic damage of blood components and activation of platelets.
Contemporary Results of Open Aortic Arch Surgery
Open aortic arch replacement can be performed with low operative mortality and stroke rates, especially in elective circumstances, by a team with particular focus on the procedure.
Wet-Priming Extracorporeal Membrane Oxygenation Device Maintains Sterility for up to 35 Days of Follow-Up
Sterility was maintained in the ECMO circuits for up to 35 days.
Nutritional Imbalances during Extracorporeal Life Support
The aim of this chapter is to describe the changes induced by artificial membranes and the required therapies to optimize nutritional support.
Variations in the Application of Various Perfusion Technologies in Great Britain and Ireland–A National Survey
This study investigates variations in the application of these technologies throughout Great Britain and Ireland (GB & I).
O2 Delivery and CO2 Production during Cardiopulmonary Bypass as Determinants of Acute Kidney Injury
The experimental hypothesis was that nadir DO2 values and nadir DO2/VCO2 ratios during CPB would be independent predictors of AKI.
From Extracorporeal Membrane Oxygenation to Ventricular Assist Device Oxygenation without Sternotomy
We report a method of minimally invasive LV drainage while the patient is receiving peripheral ECMO support and subsequent staged switch to paracorporeal LVAD without the need for a median sternotomy.
The End Organ Protection in Cardiac Surgery
Mortality and morbidity post cardiac surgery with cardiopulmonary bypass (CPB) remain relative stable over the last decades, while the number of patients with increased co-morbidity and more complex cardiac disease increases.
Clinical and Biochemical Outcomes for Additive Mesenteric and Lower Body Perfusion during Hypothermic Circulatory Arrest for Complex Total Aortic Arch Replacement Surgery
We report our experience with additive warm mesenteric and lower body perfusion (1-3 L/min, 30°C) in addition to continuous cerebral and myocardial perfusion in 5 patients who underwent total aortic arch replacement with trifurcated head vessel re-implantation and distal elephant trunk reconstruction.
The Science behind Percutaneous Hemodynamic Support: A Review and Comparison of Support Strategies
With these goals in mind, the scientific principles that govern hemodynamic effectiveness and myocardial protection as they pertain to acute support devices are reviewed.