Managing a Surgical Exsanguination Emergency in the Operating Room through Simulation: An Interdisciplinary Approach
Operating room (OR) emergencies, such as fire, anaphylaxis, cardiac arrest, and exsanguination, are infrequent, but high-risk situations that can result in significant morbidity and mortality.
Speaking up and Sharing Information Improves Trainee Neonatal Resuscitations
Teamwork behaviors of assertion and sharing information are 2 important mediators of efficiency and quality of resuscitations.
Rapamycin Protects against Myocardial Ischemia-Reperfusion Injury through JAK2-STAT3 Signaling Pathway
We propose that rapamycin is a novel and clinically relevant pharmacological strategy to target STAT3 activation for treatment of myocardial infarction.
Isoflurane Prevents Neurocognitive Dysfunction After Cardiopulmonary Bypass in Rats
Isoflurane has documented neuroprotective effects so the present authors hypothesized that isoflurane prevents the neurocognitive dysfunction in rats after CPB.
Red Blood Cell Transfusion Volume and Mortality among Patients Receiving Extracorporeal Membrane Oxygenation
Greater red blood cell transfusion volumes among patients supported with ECMO for non-cardiac indications are independently associated with an increase in odds of mortality.
Cerebral Perfusion during Cardiopulmonary Bypass in Children: Correlations between Near-Infrared Spectroscopy, Temperature, Lactate, Pump Flow, and Blood Pressure
In this study, we aimed to investigate the correlation between cerebral rSO(2) and lactate, pump flow, hematocrit, pCO(2) , and mean blood pressure (MBP) during cardiopulmonary bypass (CPB).
Review Article: Cerebral Near-Infrared Spectroscopy in Adults: A Work in Progress
Near-infrared spectroscopy (NIRS) has potential as a noninvasive brain monitor across a spectrum of disorders.
Predictive Modeling of the Virtual Hemi-Fontan Operation for Second Stage Single Ventricle Palliation: Two Patient-Specific Cases
Results demonstrate that the same operation performed in two different patients can lead to different hemodynamic characteristics, and that modeling can be used to uncover physiologic changes associated with different clinical conditions.
Pressure-Guided Positioning of Bicaval Dual-Lumen Catheters for Venovenous Extracorporeal Gas Exchange
Bicaval dual-lumen catheters allow for single-site cannulation venovenous extracorporeal gas exchange and facilitate early mobilization of patients.
The Preventative Role of Curcumin on the Lung Inflammatory Response Induced by Cardiopulmonary Bypass in Rats
We designed this study to determine whether or not curcumin inhibits TLR4 and MyD88 protein levels and ameliorates lung inflammatory injury in a rat CPB model.
Considerations on Afterload Management for Patients with Centrifugal Ventricular Assist Devices
This case report illustrates the challenges in managing patients with centrifugal ventricular assist devices (VADs).
A Hemolysis Study of an Intravascular Blood Cooling System for Localized Organ Tissue Cooling
To assess initial blood safety of our new organ cooling system, the CoolGuide Cooling System (CCS), we investigated safe operating conditions and configurations from a hemolysis perspective.