Toward Optimal Anticoagulation Monitoring During Cardiopulmonary Bypass: It Is Still A Tough “ACT”
A switch from ACT to anti-Xa monitoring cannot be recommended in cardiac surgery with CPB at the moment.
Evidence-Based Translational Research Approach May Help to Select the Best Femoral Arterial Cannula for Adolescent/Adult Extracorporeal Life Support Population
The objective of this translational study is to evaluate eight femoral arterial cannulae (Medtronic and Maquet, 15 Fr, 17 Fr and 19 Fr compared to Medos: 16 Fr and 18 Fr) using an adolescent/adult extracorporeal life support (ECLS) circuitry.
Commentary: Do-it-yourself Cell Salvage
The cause of complications observed with increased cell salvage is likely to remain enigmatic.
Multiple Electrode Aggregometry After Cardiopulmonary Bypass to Assess Platelet (Dys)-Function and Transfusion Threshold: A Concordance Study
The application of new Multiplate analyzer technologies, like the ADP test, have the potential to reduce platelet transfusion rates in cardiac surgery patients compared with the use of platelet counts alone; this point-of-care test may constitute an important strategy to help spare the use of allogeneic blood products. Additional studies are needed to confirm this trend and establish the best cutoff values to apply.
Effects of Cardiac Surgery and Salvaged Blood Transfusion on Coagulation Function Assessed by Thromboelastometry
Salvaged blood transfusion of more than 18.5% whole blood volume may impair coagulation function particularly in patients with lower FIBTEM-MCF before and after cardiac surgery.
Comparison of Postoperative Cognitive Decline in Patients Undergoing Conventional Vs Miniaturized Cardiopulmonary Bypass: A Randomized, Controlled Trial
This study shows that the MCPB was not superior to CCPB with cell salvage and biocompatible tubing with regard to the neurocognitive outcomes measured by the RBANS.
Evaluation of Arterial Stiffness in Cardiac Surgical Patients Using Applanation Tonometry
Cardiac surgery was associated with an improvement in arterial stiffness, A-V coupling, and myocardial contractility as assessed using applanation tonometry. The results suggest, however, a transient imbalance between myocardial oxygen supply and demand in the immediate postoperative period.
Development of A Real-Time Blood Damage Monitoring Device for Cardiopulmonary Bypass System Using Near-Infrared Spectroscopy
The results demonstrate the clinical potential of a real-time, low-cost, and reliable blood damage monitoring device to improve the safety of CPB operation.
Factors Influencing Activated Clotting Time Following Heparin Administration for the Initiation of Cardiopulmonary Bypass
Old age, heart failure, and lower platelet counts affected heparin activity. The dose of heparin should be considered in those patients to reach the target ACT.
Acute Oxygenator Occlusion in Two Cases of Polycythemia Vera: Bailout Strategies
We report two cases of acute and severe oxygenator failure during cardiopulmonary bypass and present valid exit scenarios.
The Blood Protective Effect of Autologous Platelet Separation in Aortic Dissection
The intraoperative auto transfusion of platelets significantly reduced the volume of allogeneic platelet transfusion after the operation for aortic dissection, which has a significant blood protective effect.
Oxygenator Impact on Voriconazole in Extracorporeal Membrane Oxygenation Circuits
Further evaluations with multiple dose in vitro and in vivo investigations are needed before specific voriconazole dosing recommendations can be made for clinical application with extracorporeal membrane oxygenation.