Blood Transfusion Practices in Cardiac Anesthesia
The aim of this review is to provide cardiac surgery specific clinically useful guidelines pertaining to transfusion triggers, optimal haemodilution during CPB, autologous blood transfusion and role of perioperative blood salvage based on available evidence.
Hemorrhage and Thrombosis with Different LVAD Technologies: A Matter of Flow
Much of the morbidity and mortality associated with ventricular assist devices (VADs) is due to haemorrhagic and thrombotic complications.
Preoperative Continuation of Aspirin Therapy May Improve Perioperative Saphenous Venous Graft Patency After Off-Pump Coronary Artery Bypass Grafting
We sought to evaluate the effect of preoperative continuation of aspirin therapy on perioperative graft patency after OPCAB.
Evaluation of a Novel Transfusion Algorithm Employing Point-of-care Coagulation Assays in Cardiac Surgery: A Retrospective Cohort Study with Interrupted Time-Series Analysis
This study evaluated a novel transfusion algorithm that uses point-of-care coagulation testing.
Risk Factors Related to Transfusion Requirements in Patients Undergoing Implantation of Ventricular Assist Devices
This is a retrospective analysis of prospectively collected data between April 2009 and June 2012. Linear regression was used to determine factors associated with increased transfusion.
Platelet Function During Cardiopulmonary Bypass Using Multiple Electrode Aggregometry: Comparison of Centrifugal and Roller Pumps
Blood trauma may be lower with centrifugal pumps (CPs) than with roller pumps (RPs) during cardiopulmonary bypass (CPB), because, unlike RPs, CPs do not compress the tubing, and shear stress is considered lower in CPs than in RPs. However, relative platelet function remains unclear. Using multiple electrode aggregometry (MEA), we compared platelet function with CP and RP.
Evidence-Based Use of FFP: the Influence of a Priming Strategy Without FFP During CPB on Postoperative Coagulation and Recovery in Pediatric Patients
Our present study observed the effects of a priming strategy without fresh frozen plasma (FFP) during cardiopulmonary bypass (CPB) on postoperative coagulation and clinical recovery in pediatric patients, aiming to supply new evidence for evidence-based use of FFP.
Protamine Requirements in Cardiac Surgery: Effect of Changes in the Heparin Reference Standard
UFH (unfractionated heparin) and protamine are integral to cardiac surgery, and inappropriate dosing can predispose to coagulopathy and hemorrhage.
Pathophysiology of Cardiopulmonary Bypass: Current Strategies for the Prevention and Treatment of Anemia, Coagulopathy, and Organ Dysfunction
In this review, pathophysiological aspects of CPB are considered from a practical point of view, and preventive strategies for hemodilutional anemia, coagulopathy, inflammation, metabolic derangement, and neurocognitive and renal dysfunction are discussed.
A Polymicrobial Outbreak of Surgical Site Infections following Cardiac Surgery at a Community Hospital in Florida, 2011-2012
We describe an outbreak of 22 sternal surgical site infections following cardiac surgery
Magnitude of Anemia at Discharge Increases 30-Day Hospital Readmissions
Anemia during hospitalization is associated with poor health outcomes
Safety, Efficacy and Response to a Hydrocortisone Rescue Therapy Protocol in Children with Refractory Hypotension After Cardiopulmonal Bypass
Little is known about which paediatric patients respond to hydrocortisone rescue therapy