The Effect of Dilution on Plasma Coagulation Kinetics Determined by Thrombelastography Is Dependent on Antithrombin Activity and Mode of Activation
We determined that decreased antithrombin activity is responsible for accelerated clot initiation via thrombelastography with in vitro plasma-based experiments. Celite activation of plasma resulted in a linear relationship between degree of dilution and thrombelastographic variables.
Congenital and Acquired Thrombocytopenia
The diagnosis and management of thrombocytopenia is a growing component in the practice of hematology. The frequency with which hematologists are called […]
A Closed Perfusion System With Heparin Coating and Centrifugal Pump Improves Cardiopulmonary Bypass Biocompatibility in Elderly Patients
The results suggest that a closed perfusion system with a heparin-coated circuit and a centrifugal pump may improve cardiopulmonary bypass biocompatibility in elderly cardiac surgery patients in comparison with a conventional system.
The Response to Activated Protein C After Cardiopulmonary Bypass: Impact of Factor V Leiden
Patients without factor V Leiden (FVL) have increased sensitivity to the activated protein C after cardiac surgery, whereas FVL carriers do not.
Database Review of Possible Factors Influencing Point-of-Care Platelet Gel Manufacture
In this study, an attempt is made to isolate factors that are important in developing a consistent gel.
Decline in Cardiovascular Disease Reported in Patients With Diabetes
Adults with diabetes have experienced a 50 percent decline in the incidence rate for cardiovascular disease events in recent decades, according to a report in the November 24 issue of JAMA.
“Awake” CABG Using Internal Thoracic Arteries Safe for Multivessel Disease
"Awake" coronary artery bypass grafting (CABG) using the internal thoracic arteries is a feasible and safe procedure for double or triple vessel disease, findings from a small study suggest.
A Modified Method for Preparing Platelet-Rich Plasma: An Experimental Study
It was experimentally shown that PRP with high platelet counts can be prepared using this modified method without the need for costly autotransfusion systems.
Diagnostic Score for Heparin-Induced Thrombocytopenia After Cardiopulmonary Bypass
Heparin-induced thrombocytopenia (HIT) occurs in nearly 3% of patients treated with heparin after cardiopulmonary bypass (CPB).
A Perfusionist’s Role in Lung Transplant Preservation
As organ transplant surgery continues to grow, effective organ preservation techniques and technology will expand as well.
Platelet Quantification and Growth Factor Analysis from Platelet Rich Plasma: Implications for Wound Healing
Sufficient concentrates and release of these growth factors through autologous platelet gels may be capable of expediting wound healing in a variety of as yet undetermined specific wound applications.
Hematological Changes During Short-Term Tidal Flow Extracorporeal Life Support
Single occluder tidal flow ECLS may be feasible and efficacious for long-term application once recirculation is resolved and the system evaluated for long-term support.