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Hemoglobin-Driven Pathophysiology is an in Vivo Consequence of the Red Blood Cell Storage Lesion that can be Attenuated in Guinea Pigs by Haptoglobin Therapy
Pathologies observed after transfusion with old blood, together with the favorable response to Hp supplementation, allowed us to define the in vivo consequences of the rbc storage lesion as storage-related posttransfusion hemolysis producing Hb-driven pathophysiology. Hb sequestration by Hp might therefore be a therapeutic modality for enhancing transfusion safety in severely ill or massively transfused patients.
Platelet-Rich Fibrin: Evolution of a Second-Generation Platelet Concentrate
This article describes the evolution of this novel platelet concentrate, referred to as PRF.
Predictors and Outcomes of Coronary Artery Bypass Grafting: A Systematic and Untargeted Analysis of More Than 120,000 Individuals and 1,300 Disease Traits
Known CVD risk factors associate most strongly with incident CABG. However, CABG is associated with increased risk of several, somewhat unexpected, non-CVD traits. More detailed study of these links is warranted to establish potential causality and pathogenesis.
