Transfusion-Free Cardiopulmonary Bypass in Jehovah’s Witness Patients Weighing Less than 5 Kg
We report the use of cardiopulmonary bypass (CPB) during open-heart surgery in three infants with a body weight of 4.5 kg, 3.5 kg, and 3.1 kg, respectively, without transfusion of blood components.
Cerebral Oximetry During Cardiac Surgery: The Association Between Cerebral Oxygen Saturation and Perioperative Patient Variables
This "real-world" study was designed to assess the patterns of regional cerebral oxygen saturation (rSO(2)) change during adult cardiac surgery. A secondary objective was to determine any relation between perioperative rSO(2) (baseline and during surgery) and patient characteristics or intraoperative variables.
Fibrinogen Concentration Significantly Decreases After On-Pump Versus Off-Pump Coronary Artery Bypass Surgery: A Systematic Point-of-Care ROTEM Analysis
Studies have emphasized the importance of normal fibrinogen concentrations in surgical patients. The primary hypothesis of this study was that fibrinogen levels significantly decrease in on-pump coronary artery bypass graft (CABG) surgery versus off-pump coronary artery bypass graft (OPCAB) surgery. The second objective was to show that ROTEM (TEM International, GmbH, Munich, Germany) rapidly detects these abnormalities compared with standard tests.
Retrograde Autologous Priming for Cardiopulmonary Bypass: A Safe and Effective Means of Decreasing Hemodilution and Transfusion Requirements
The obligatory hemodilution resulting from crystalloid priming of the cardiopulmonary bypass circuit represents a major risk factor for blood transfusion in cardiac operations. We therefore examined whether retrograde autologous priming of the bypass circuit would result in decreased hemodilution and red cell transfusion.
Retrograde Autologous Priming of the Cardiopulmonary Bypass Circuit: Safety and Impact on Postoperative Outcomes
Retrograde autologous priming (RAP) is a blood conservation technique used to limit the severity of hemodilution during cardiopulmonary bypass and reduce perioperative transfusions. The aim of this investigation was to examine the safety of RAP and to determine the effect of RAP on adverse outcomes after cardiac surgery.
Autologous Priming Technique to Reduce Blood Transfusion in Pediatric Cardiopulmonary Bypass
Autologous priming of the extracorporeal circuit used in conjunction with ultrafiltration, pharmacologic manipulation, and cell salvage may decrease the need for blood transfusion in the pediatric cardiac surgical population.
Combination of Autologous Transfusion and Retrograde Autologous Priming Decreases Blood Requirements
In a prospective study, 60 patients posted for coronary artery bypass graft (CABG) surgery on cardiopulmonary bypass (CPB) were assigned to 2 groups of 30 each. (group A =combination of acute normovolaemic haemodilution (ANH) and retrograde autologous priming (RAP), group B=control). The aim was to investigate whether retrograde autologous priming reduces haemoditution as compared to control cases.
Intraoperative Autologous Blood Donation and Retrograde Autologous Priming for Cardiopulmonary Bypass: A Safe and Effective Technique for Blood Conservation
Haemodilution resulting from crystalloid priming of the cardiopulmonary bypass (CPB) circuit is one of the important reasons for blood transfusion in cardiac surgery, especially in patients with low body surface area (BSA).
The Effect of Retrograde Autologous Priming of the Cardiopulmonary Bypass Circuit on Cerebral Oxygenation
The aim of this study was to investigate the effect of retrograde autologous priming (RAP) of the cardiopulmonary bypass (CPB) circuit on cerebral oxygenation.
Retrograde Autologous Priming and Allogeneic Blood Transfusions: A Meta-Analysis
A literature review and meta-analysis were undertaken to assess the clinical effectiveness of retrograde autologous priming of the cardiopulmonary bypass circuit to reduce allogeneic packed red blood transfusions in adult cardiac surgery.
Retrograde Autologous Priming of the Cardiopulmonary Bypass Circuit Reduces Blood Transfusion in Small Adults: a Prospective, Randomized Trial
Extreme haemodilution occurring with cardiopulmonary bypass imposes a primary risk factor for blood transfusion in small adult cardiac surgical patients. Priming of the cardiopulmonary bypass circuit with patients' own blood [retrograde autologous priming (RAP)] is a technique used to limit haemodilution and reduce transfusion requirements.
Factors that Influence the Ability to Perform Autologous Priming
The purpose of this study was to determine which factors impact the ability to perform autologous priming (AP) of the extracorporeal circuit.