Optimization of Thromboelastography-Guided Platelet Transfusion in Cardiovascular Surgery
Use of a TEG-guided transfusion protocol dramatically reduced PT after CPB, particularly in patients undergoing aortic arch aneurysm repair.
Is There a Suitable Method of Anticoagulation in Pregnant Patients with Mechanical Prosthetic Heart Valves?
A best evidence topic was written according to a structured protocol in order to identify the mode of anticoagulation that has the best safety profile for both the mother and the foetus in pregnant patients with mechanical prosthetic heart valves.
The Role of the VAD Perfusionist (EP Video)
Christopher Pierce discusses the new role of the VAD perfusionist (26:28 minutes).
Acute Massive Pulmonary Embolism and Hemodynamic Collapse in an 11 Week Post Cesarean Section Patient (EP Video)
Jenna Cornibe presents a case report on a patient 11 Week post cesarean section patient with a pulmonary embolism (27:54 minutes).
Platelet Mapping as Part of Modified Thromboelastography (TEG) in Patients Undergoing Cardiac Surgery and Cardiopulmonary Bypass
The platelet-mapping assay of the thromboelastograph was used to measure platelet aggregation and to examine the effect of cardiopulmonary bypass on multiple platelet receptors and the role of altered receptor activity in postoperative bleeding.
A Method for Anticoagulation of Children on Mechanical Circulatory Support
We describe an anticoagulation protocol based upon TEG and platelet aggregation studies and using heparin, aspirin, and dipyridamole. Adequate anticoagulation is more difficult in children. However, 71% of the patients in our study survived long term.
Thrombelastography Change after Bridging to Left Ventricular Assist Device From Extracorporeal Membrane Oxygenation Patients
Coagulopathy of patients with VAD improved after bridging from ECMO, which can be attributed to improved coagulation factor and platelet function. Thus, bleeding complications are reduced.
Impact of Cell Salvage During Cardiac Surgery on the Thrombelastomeric Coagulation Profile: A Pilot Study
Intraoperative cell salvage of the cardiopulmonary bypass residual volume can dilute platelets and coagulation factors. This is a report of a randomised control trial of 20 patients undergoing coronary bypass surgery.
A Randomized Prospective Analysis of Alteration of Hemostatic Function in Patients Receiving Tranexamic Acid and Hydroxyethyl Starch Undergoing Off Pump Coronary Artery Bypass Surgery
Postoperative hemorrhagic complications is still one of the major problems in cardiac surgeries. It may be caused by surgical issues, coagulopathy caused by the side effects of the intravenous fluids administered to produce plasma volume expansion such as hydroxyl ethyl starch (HES).
Bivalirudin-Based Versus Conventional Heparin Anticoagulation for Postcardiotomy Extracorporeal Membrane Oxygenation
The present study is a retrospective comparison of the conventional heparin-based anticoagulation protocol with a bivalirudin-based, heparin-free protocol. Endpoints of this study are blood loss, allogeneic blood product use, and costs during the ECMO procedure.
Antiplatelet Therapy in Patients with Coronary Artery Stents for Noncardiac Surgery: Role of Thromboelastography
The perioperative course of the patients who have undergone coronary stent placement was studied. These patients were on dual antiplatelet therapy and were posted for noncardiac surgery.
Monitoring Patients at Risk of Massive Transfusion with Thrombelastography or Thromboelastometry: A Systematic Review
Thrombelastography (TEG) and Thrombelastometry (ROTEM) are viscoelastic whole-blood assays evaluating the haemostatic capacity of blood. These devices are used in algorithms to guide transfusion of haemostatic blood components.