Efficacy of Tranexamic Acid in Paediatric Cardiac Surgery: A Systematic Review and Meta-Analysis
Evidence supporting the routine use of TXA in paediatric cardiac surgery remains weak.
Hyperfibrinolysis is Common in Out-of-Hospital Cardiac Arrest: Results from a Prospective Observational Thromboelastometry Study
Routine use of fibrinolytic therapy in all patients with prolonged CPR cannot therefore be recommended.
An Assessment of Thromboelastometry to Monitor Blood Coagulation and Guide Transfusion Support in Liver Transplantation
This study was aimed at assessing the value of TEM in monitoring blood coagulation and guide transfusion support in OLT.
Sustained Heparin Effect Contributes to Reduced Plasma Thrombin Generation Capacity Early after Cardiac Surgery
A marked reduction in thrombin generation potential was observed in the early postoperative phase after cardiac surgery.
Pharmacokinetics of Tranexamic Acid in Patients Undergoing Cardiac Surgery with Use of Cardiopulmonary Bypass
We conducted a study to assess pharmacokinetics of high-dose tranexamic acid for 24 h after administration of the drug in patients undergoing cardiac surgery with cardiopulmonary bypass.
Effect of a Single Bolus of Methylene Blue Prophylaxis on Vasopressor and Transfusion Requirement in Infective Endocarditis Patients Undergoing Cardiac Surgery
We aimed to evaluate the effect of prophylactic MB administration before CPB on vasopressor and transfusion requirements in patients with IE undergoing valvular heart surgery (VHS).
Platelet Mapping as Part of Modified Thromboelastography (TEG®) in Patients Undergoing Cardiac Surgery and Cardiopulmonary Bypass
The platelet-mapping assay of the thromboelastograph was used to measure platelet aggregation and to examine the effect of cardiopulmonary bypass on multiple platelet receptors and the role of altered receptor activity in postoperative bleeding.
Perioperative Red Blood Cell Transfusion: Harmful or Beneficial to the Patient?
This review focuses on the physiology of oxygen transport, the hazards of acute anemia, the hazards of RBC transfusion, and the literature putting these problems into perspective.
Prohemostatic Treatment in Cardiac Surgery
This article will discuss pharmacological agents including antifibrinolytics, protamine, desmopressin, fibrinogen, purified protein concentrates, recombinant factor VIIa, factor XIII, and topical agents used in cardiac surgery.
Early Platelet Dysfunction: An Unrecognized Role in the Acute Coagulopathy of Trauma
In this study, we show that platelet dysfunction is manifest after major trauma and before substantial fluid or blood administration.
An Original Model to Predict Intensive Care Unit Length-of Stay after Cardiac Surgery in a Competing Risk Framework
ICU-LOS can be predicted by preoperative data and type of surgeries.
Reoperation for Bleeding in Cardiac Surgery
To reduce the rate of reoperations and mortality due to postoperative bleeding, we aim to identify risk factors that predict reoperation.