Mechanical Prosthetic Mitral Valve Thrombosis in a First Trimester Pregnant Woman
We briefly review the different anticoagulation options during pregnancy and perfusion strategies on CPB to improve fetal outcomes.
Emergency Tricuspid Valve Replacement During Pregnancy
High-flow (> 3.0 L/min(2)), high-pressure (> 70 mmHg), normothermic CPB using pulsatile flow and blood cardioplegia is thought to offer the best outcome to the fetus, although data to support these claims are not compelling.
Medical Management of Thoracic Aortic Aneurysm Disease
Lifestyle modification is also important for patients with thoracic aortic aneurysm, including restrictions on physical activity, weight lifting, and recommendations about the management of pregnancy. Long-term surveillance of the aorta, even after successful surgery, is necessary for timing of prophylactic surgery and to evaluate for late complications.
Open Cardiac Surgery in the First Hours of Life Using Autologous Umbilical Cord Blood
The use of autologous umbilical cord blood is feasible in neonatal open heart surgery. Complete surgical repair of complex critical CHD can be applied successfully to neonates within the first hours of life.
Anaestheia for Valve Replacement in the Second Trimester of Pregnancy
The case is presented of a 19 weeks pregnant woman, who required a mitral valve replacement, which was achieved with success, and enabled her to complete her pregnancy without complications. Details are provided on the published references on which our management was based.
Acute Type II Aortic Dissection with Severe Aortic Regurgitation and Chronic Descending Aortic Dissection in Pregnant Patient with Marfan Syndrome
This case report involves a successful Bentall procedure for and recovery from a rare aortic dissection in a pregnant Marfan patient who developed acute type II aortic dissection with severe aortic regurgitation and chronic descending aortic dissection immediately after Cesarean section.
Moderate Versus Deep Hypothermia for the Arterial Switch Operation–Experience with 100 Consecutive Patients
Evaluated the impact of moderate versus deep perioperative hypothermia on postoperative morbidity in patients receiving the arterial switch operation (ASO).
CPB-Assisted Aortic Valve Replacement in a Pregnant 27-year-old with Endocarditis
A 27-year-old, G(3)P( 2)A(0) female with acute Staph aureus (SA) endocarditis successfully underwent CPB-assisted aortic valve replacement with a bioprosthetic aortic valve at 22 weeks' gestation.
Pregnancy in Marfan Syndrome After Aortic Root Replacement: A Case Report and Review of the Literature
Successful pregnancy and delivery can be achieved in Marfan's patients after aortic root replacement.
Perioperative Coagulation Management During Cardiac Surgery
Prospective randomized multicenter studies are needed to confirm the hypothesis that algorithm-based specific hemotherapy in conjunction with POC testing minimizes patient's exposure to blood products and improves clinical outcome.
The Future:Therapy of Myocardial Protection
Recent studies have proposed that old, inexpensive drugs--in human use for decades (e.g., β-blockers and cyclosporine, among others)--can reduce ischemia/reperfusion injury, I/R injury, when administered intravenously before coronary opening. The demonstration of such a cardioprotective effect should have a significant impact in the care of AMI patients.
Cyclosporine A Normalizes Mitochondrial Coupling, Reactive Oxygen Species Production, and Inflammation and Partially Restores Skeletal Muscle Maximal Oxidative Capacity in Experimental Aortic Cross-Clamping
Cyclosporine A normalized ROS production, decreased inflammation, and restored mitochondrial coupling during aortic cross-clamping. Incomplete V(max) protection might be due to low cyclophilin D expression in gastrocnemius, preventing CsA from blocking mPTP opening.