Stromal Cells from the Adipose Tissue-Derived Stromal Vascular Fraction and Culture Expanded AdiposeTissue-Derived Stromal/Stem Cells: A Joint Statement of the International Federation for Adipose Therapeutics (IFATS) and Science and the International So
The goal of this paper is to provide initial guidance for the scientific community working with adipose-derived cells and to facilitate development of international standards based on reproducible parameters.
Long-Term Detection of Human Adipose Derived Mesenchymal Stem Cells After Intra-Articular Injection
These data argue for the feasibility and safety of using intra-articular (IA) delivery of human adipose-derived stem cell (hASC) for the treatment of rheumatic diseases affecting the joints.
Adipose-Derived Stem Cells Weigh in as Novel Therapeutics for Acute Lung Injury
We discuss the advantages and potential limitations of using adipose-derived stem cells as therapeutics for human acute lung injury.
Mesenchymal Stem Cell Therapy in Osteoarthritis: Advanced Tissue Repair or Intervention with Smouldering Synovial Activation
Desando and co-workers report in Arthritis Research & Therapy that intra-articular delivery of adipose-derived stem cells attenuates progression of synovial activation and joint destruction in osteoarthritis in an experimental rabbit model. Clinical studies are warranted to see whether this approach might be a novel way to combat development of joint destruction in inflammatory subtypes of osteoarthritis.
Extracts of Adipose Derived Stem Cells Slows Progression in the R6/2 Model of Huntington’s Disease
Stem cell transplantation has been investigated as a therapeutic strategy to treat the Huntington's disease (HD). Considering clinical feasibility and safety, injection of cell-free extracts of ASCs (ASCs-E) could be effective and safe strategy for HD patients, comparable to the stem cell therapy. Findings from our study provide possible strategy to inhibit HD progression and reasonable resources for treatment.
Decreased Erythrocyte Deformability After Transfusion and the Effects of Erythrocyte Storage Duration
The findings demonstrate that increased duration of erythrocyte storage is associated with decreased cell membrane deformability and that these changes are not readily reversible after transfusion.
Outcomes of Less Invasive J-Incision Approach to Aortic Valve Surgery
Within that portion of the spectrum of isolated aortic valve surgery where propensity matching was possible, minimally invasive aortic valve surgery had not only cosmetic advantages, but blood product use, respiratory, pain, and resource utilization advantages over full sternotomy, and no apparent detriments.
Noise Levels in Modern Operating Rooms During Surgery
This study consistently showed that noise in the operating room is louder during the critical anesthesia components of the case.
Regenerate Augmentation with Bone Marrow Concentrate after Traumatic Bone Loss
The aim of this feasibility study was to investigate the potential of bone marrow aspiration concentrate (BMAC) for percutaneous regenerate augmentation to accelerate bony consolidation of the regenerate.
Establishing proof of concept: Platelet-Rich Plasma and Bone Marrow Aspirate Concentrate may Improve Cartilage Repair Following Surgical Treatment for Osteochondral Lesions of the Talus
The basic science literature therefore establishes the proof of concept that biological adjuncts may improve cartilage repair when used in conjunction with reparative and replacement treatment strategies for osteochondral lesions of the talus.
In Vivo Comparison of the Bone Regeneration Capability of Human Bone Marrow Concentrates vs. Platelet-Rich Plasma
The objective of this study was to evaluate the effects of human BMAC and PRP in combination with β-tricalcium phosphate (β-TCP) on promoting initial bone augmentation in an immunodeficient mouse model.
The Positive Effects of Different platelet-Rich Plasma Methods on Human Muscle, Bone, and Tendon Cells
The primary findings of this study suggest the application of different PRP separations may result in a potential beneficial effect on the clinically relevant target cells in vitro.