History and Use of del Nido Cardioplegia Solution at Boston Children’s Hospital
We present the developmental history, supporting theory, and current protocol for use of what is now referred to as del Nido cardioplegia.
Exercise and the Platelet Activator Calcium Chloride both Influence the Growth Factor Content of Platelet-Rich Plasma (PRP): Overlooked Biochemical Factors that Could Influence PRP Treatment
The first aim of this study was to evaluate the effect of exercise on platelet and platelet-derived growth factors (PDGF)-AB, hepatocyte growth factor (HGF), insulin-like growth factor-1 (IGF-1) and vascular endothelial growth factor (VEGF) concentrations in PRP. The second aim was to study the effect of the activating agent calcium chloride (CaCl2) on growth factor concentration in relation to different exercise states.
Perioperative Nitroprusside Infusion in a Patient With Severe Aortic Stenosis: Another Component of Afterload Reduction Uncovered
The traditional goals of perioperative management of severe aortic stenosis are based on maintaining a high systemic vascular resistance (SVR) to allow for good coronary perfusion.
The Role of Transforming Growth Factor-Beta in Marfan Syndrome
The aim of this review is to review the already known features of the cellular signal transduction downstream to TGF-b and its impact on the tissue homeostasis of microfibrils, and elastic fibers.
The Combined Use of Transmyocardial Laser Revascularisation and Intramyocardial Injection of Bone-Marrow Derived Stem Cells in Patients with End-Stage Coronary Artery Disease: One Year Follow-Up
There are a growing number of patients with end-stage coronary artery disease (CAD) and refractory angina. Angiogenesis may be induced by intramyocardial injection of autologous bone marrow stem cells, intensified by inflammationaround channels performed by laser.
Total Surgical Aortic Arch Replacement as a Safe Strategy to Treat Complex Multi-segmental Proximal Thoracic Aortic Pathology
This study analyzed the results after elective open total aortic arch replacement analyzing 39 patients (median age 63 years, median logistic EuroSCORE 18.4) who underwent elective open total arch replacement between 2005 and 2012.
Pharmacologic Tools to Reduce Bleeding in Surgery
Strategies to reduce blood loss and the need for transfusions in surgery include enhancement of coagulation, inhibition of fibrinolysis, and an improved decision algorithm for transfusion based on bedside monitoring of global hemostasis.
Coronary Artery Bypass Grafting after Aprotinin: Are We Doing Better?
Accordingly, the usage of aprotinin should be reconsidered for treatment among cohorts of low-risk cardiac patients.
Variation in Ventilation Time After Coronary Artery Bypass Grafting: An Analysis From The Society of Thoracic Surgeons Adult Cardiac Surgery Database
After adjustment for severity of illness, substantial inter-center variation exists in postoperative ventilation time in this subset of patients undergoing isolated CABG.
Trends in Aortic Clamp Use during Coronary Artery Bypass Surgery: Effect of Aortic Clamping Strategies on Neurologic Outcomes
The purpose of the present study was to determine the effect of different clamping strategies during coronary artery bypass grafting on the incidence of postoperative stroke.
Quality, Patient Safety, and the Cardiac Surgical Team
This article reviews a decade of discussion surrounding quality and safety issues in cardiac surgery
Depicting Adverse Events in Cardiac Theatre: The Preliminary Conception of the RECORD Model
This article aims to raise awareness for safety measures in the cardiac surgical room