Red Blood Cell Transfusion Volume and Mortality among Patients Receiving Extracorporeal Membrane Oxygenation
Greater red blood cell transfusion volumes among patients supported with ECMO for non-cardiac indications are independently associated with an increase in odds of mortality.
Perioperative Coagulation Management During Cardiac Surgery
Recent studies suggest that implementation of point-of-care testing in hemotherapy algorithms which inclose stepwise therapeutic escalation may reduce perioperative blood loss and the transfusion rate of allogenic blood products. This should improve patient's clinical outcome and reduce costs.
Exercise-Based Cardiac Rehabilitation Improves Hemodynamic Responses After Coronary Artery Bypass Graft Surgery
Cardiac rehabilitation significantly improves functional capacity and some hemodynamic responses post coronary artery bypass grafting. Therefore, patients need to be referred to rehabilitation units.
Does Anemia Impact Hospital Readmissions after Coronary Artery Bypass Surgery
We conducted a single-center retrospective study of 2102 patients who had CABG in Ontario to determine whether anemia at hospital discharge was associated with increased 30-day hospital readmissions, readmission secondary to cardiac disease, and 30-day mortality using administrative data.
Impact of Experimental Haemodilution on Platelet Function, Thrombin Generation and Clot Firmness: Effects of Different Coagulation Factor Concentrates
The haemostatic alterations caused by haemodilution are multifactorial and affect both blood cells and coagulation.
In Vitro Comparison of Two Different Methods of Cell Washing
The objective of this study was to compare the product created by washing a unit of RBCs with the AutoLog autotransfusion device in the operating room to the washed products from a standard cell washer in the blood bank.
Thrombin Generation Assay: A New Tool to Predict and Optimize Clinical Outcome in Cardiovascular Patients?
In this review we provide a brief description of the assay and we summarize the principals of previous studies by analyzing the relationship between anticoagulant drugs and TGA.
Impact of Major Bleeding and Blood Transfusions after Cardiac Surgery: Analysis from the Acute Catheterization and Urgent Intervention Triage Strategy (ACUITY) Trial
In patients with acute coronary syndromes, RBC transfusion of ≥4 U after CABG is strongly associated with subsequent mortality.
Advances in Platelet Function Testing Assessing Bleeding Complications in Patients with Coronary Artery Disease
The present manuscript will review the prognostic value of platelet function testing to identify patients with CAD at risk of bleeding complications and the potential applications of these tests in the modern era of antiplatelet pharmacotherapy.
Antiplatelet Drugs: Mechanisms and Risks of Bleeding Following Cardiac Operations
We hypothesize that review of available evidence regarding drug-related bleeding risk, underlying mechanisms of platelet dysfunction, and variations in patient response to antiplatelet drugs will aid surgeons as they assess preoperative risk and attempt to limit perioperative bleeding.
Red Blood Cell Transfusions Worsen the Outcomes Even in Critically Ill Patients Undergoing a Restrictive Transfusion Strategy
This study aimed to evaluate epidemiology and outcomes among critically ill patients under a restrictive transfusion strategy.
Blood Transfusion and the Risk of Acute Kidney Injury After Transcatheter Aortic Valve Implantation
Blood transfusion is associated with acute kidney injury (AKI) after transcatheter aortic valve implantation (TAVI).