An Orthopedic Tissue Adhesive for Targeted Delivery of Intraoperative Biologics
One emerging therapeutic trend in orthopedics is the use of intraoperative biologics (IOB), such as bone marrow (BM) and platelet-rich plasma (PRP), to stimulate healing. Here, we introduce the application of the biomaterial chondroitin sulfate succinimidyl succinate (CS-NHS) to deliver IOB in a hydrogel adhesive.
PRP as a New Approach to Prevent Infection: Preparation and in Vitro Antimicrobial Properties of PRP
In this study, we disclose a new strategy that may be effective in preventing implant-associated infection based on the potential antimicrobial properties of platelet-rich plasma (PRP). Due to its well-studied properties for promoting healing, PRP (a biological product) has been increasingly used for clinical applications including orthopaedic surgeries, periodontal and oral surgeries, maxillofacial surgeries, plastic surgeries, sports medicine, etc.
Use of Intraoperative Cell-salvage for Autologous Blood Transfusions in Metastatic Spine Tumour Surgery: A Systematic Review
We systematically reviewed studies on intraoperative cell salvage (IOCS) in oncological surgery to investigate whether sufficient evidence exists to support its use in metastatic spine tumor surgery (MSTS) or metastatic musculoskeletal tumor surgery (MMTS).
Influence of the Washing Program on the Blood Processing Performance of a Continuous Autotransfusion Device
The continuous auto transfusion system has been widely used in surgical operations. Although the continuous autotransfusion device provided consistent hematocrit quality, the levels of some blood lipid components showed significant differences among the washing programs.
Effects of Autologous Priming on Blood Conservation after Cardiac Surgery
The objective of this study was to determine whether a protocol of retrograde autologous prime (RAP) and venous antegrade prime (VAP) reduces the need for blood transfusion and increases the hematocrit following cardiac surgery.
Post-operative Blood Management Strategies for Total Hip Arthroplasty
Our aim was to provide a broad overview of the widely used methods for reducing post-operative blood loss after total hip arthroplasty.
Effectiveness of Autologous Transfusion System in Primary Total Hip and Knee Arthroplasty
The current study analyzed the efficacy of autologous transfusion with washed shed blood (WSB) in primary total knee and total hip arthroplasty (TKA, THA).
Pre-Operative Autologous Blood Donation Versus No Blood Donation in Total Knee Arthroplasty: A Prospective Randomised Trial
In this prospective randomized study we have evaluated the efficacy of pre-operative autologous blood donation (PABD) in patients undergoing total knee arthroplasty (TKA) to answer the question whether there is any need for autologous blood donations during TKA and, if yes, for which group of patients.
Prescriptive Patient Extracorporeal Circuit and Oxygenator Sizing Reduces Hemodilution and Allogeneic Blood Product Transfusion during Adult Cardiac Surgery
The goal of this cardiopulmonary bypass (CPB) quality improvement initiative was to maximize hemoglobin nadir concentration
Outcomes and Biochemical Parameters following Cardiac Surgery: Effects of Transfusion of Residual Blood using Centrifugation and Multiple-Pass Hemoconcentration
To determine whether or not there was a significant difference between the methods of centrifugation (CF) and multiple-pass hemoconcentration (MPH) of the residual cardiopulmonary-bypass volume in relation to biochemical measurements and patient outcomes.
Bridging Anti Platelet Therapy in Patients Requiring Cardiac and Non-Cardiac Surgery: From Bench to Bedside
This article explores the theoretical background and rationale for bridging patients on antiplatelet drugs to their surgical procedure, and provides insights on how patient and procedural characteristics translate into different considerations for the use of antithrombotic agents in the surgical setting.
The Relationship between Low Intraoperative Hematocrit Levels during Cardiopulmonary Bypass and Postoperative Neurological Events
The objective of our study is to analyze whether low intraoperative hematocrit levels have an effect upon postoperative neurological events.