Equine Tendonitis Therapy Using Mesenchymal Stem Cells and Platelet Concentrates: A Randomized Controlled Trial
Tendon injury is a major cause of lameness and decreased performance in athletic equines. Various therapies for tendonitis have been described; however, none of these therapies results in complete tissue regeneration, and the injury recurrence rate is high even after long recovery periods involving rest and physiotherapy.
Bacteriostatic Effect of Equine Pure Platelet-Rich Plasma and Other Blood Products Against Methicillin-Sensitive Staphylococcus Aureus. An In Vitro Study
We evaluated the bacteriostatic in vitro effect of pure platelet-rich plasma (P-PRP), pure platelet-rich gel (P-PRG), leukocyte-poor gel(LPG), platelet-poor plasma (PPP), and heat inactivated plasma (IP) against methicillin-sensitive Staphylococcus aureus (MSSA) over a period of 24 hours.
Effects of the Breed, Sex and Age on Cellular Content and Growth Factor Release from Equine Pure-Platelet Rich Plasma and Pure-Platelet Rich Gel
The objectives of this study were: 1) to compare the cellular composition of P-PRP with whole blood and platelet poor plasma (PPP); 2) to compare the concentration of transforming GF beta 1 (TGF-β1) and platelet derived GF isoform BB (PDGF-BB) between P-PRP treated with non-ionic detergent (P-PRP+NID), P-PRG (activated with calcium gluconate -CG-), PPP+NID, PPP gel (PPG), and plasma and; 3) to evaluate and to correlate the effect of the breed, gender and age on the cellular and GF concentration for each blood component.
Perioperative Considerations in a Sickle Cell Patient Undergoing Cardiopulmonary Bypass
An 11-year-old child, a known case of sickle cell anaemia with a history suggestive of sickling crisis in the past was scheduled for surgical pulmonary valvotomy.
Does Incorporation of Thromboelastography Improve Bleeding Prediction following Adult Cardiac Surgery?
We investigated whether the addition of TEG parameters to a clinically based bleeding model would improve the predictability of postoperative bleeding
The Influence of Drugs Used in Cardiac Anaesthesia and Critical Care on Multiple Electrode Aggregometry: An In-Vitro Volunteer Study
. In patients treated with high to normal doses of magnesium, MEA results for ADP and TRAP-tests should be interpreted with caution.
Hypothermic Cardiopulmonary Bypass Without Exchange Transfusion in Sickle-Cell Patients: A Matched-Pair Analysis
Sickle-cell patients undergo cardiopulmonary bypass (CPB) surgery in our institution without perioperative exchange transfusion. We sought to determine whether this protocol increased mortality or important sickle-cell-related complications.
The Influence of Heparin Resistance on Postoperative Complications in Patients Undergoing Coronary Surgery
Heparin resistance is relatively frequent in patients undergoing coronary surgery. We aimed to assess the impact of heparinresistance on the outcome of patients undergoing coronary surgery with cardiopulmonary bypass (CABG). Three definitions of heparin resistance were adopted.
Preoperative Anemia Increases Mortality and Postoperative Morbidity after Cardiac Surgery
This study evaluates the effect of preoperative anemia on early clinical outcomes in patients undergoing cardiac surgery.
A Randomized, Double Blind Trial of Prophylactic Fibrinogen to Reduce Bleeding in Cardiac Surgery
Postoperative bleeding has a great clinical importance and can contribute to increased mortality and morbidity in patients undergoing coronary artery bypass graft surgery. In this prospective, randomized, double-blind study, we evaluated the effect of prophylactic administration of fibrinogen concentrate on post-coronary artery bypass graft surgery bleeding.
Is There Evidence that Fresh Frozen Plasma is Superior to Antithrombin Administration to Treat Heparin Resistance in Cardiac Surgery?
A best evidence topic in cardiac surgery was written according to a structured protocol. The question addressed was, 'in [patients with heparinresistance] is [treatment with FFP] superior [to antithrombin administration] in [achieving adequate anticoagulation to facilitate safe cardiopulmonary bypass]?'
Incremental Value of Anemia in Cardiac Surgical Risk Prediction With the European System for Cardiac Operative Risk Evaluation (EuroSCORE) II Model
Anemia is a risk factor for adverse events after cardiac operations. We evaluated the incremental value of preoperative anemia over the European System for Cardiac Operative Risk Evaluation (EuroSCORE) II to predict hospital death after cardiac operations.