Pathophysiology of Cardiopulmonary Bypass: Current Strategies for the Prevention and Treatment of Anemia, Coagulopathy, and Organ Dysfunction
In this review, pathophysiological aspects of CPB are considered from a practical point of view, and preventive strategies for hemodilutional anemia, coagulopathy, inflammation, metabolic derangement, and neurocognitive and renal dysfunction are discussed.
Evidence-Based Use of FFP: the Influence of a Priming Strategy Without FFP During CPB on Postoperative Coagulation and Recovery in Pediatric Patients
Our present study observed the effects of a priming strategy without fresh frozen plasma (FFP) during cardiopulmonary bypass (CPB) on postoperative coagulation and clinical recovery in pediatric patients, aiming to supply new evidence for evidence-based use of FFP.
Protamine Requirements in Cardiac Surgery: Effect of Changes in the Heparin Reference Standard
UFH (unfractionated heparin) and protamine are integral to cardiac surgery, and inappropriate dosing can predispose to coagulopathy and hemorrhage.
Platelet Function During Cardiopulmonary Bypass Using Multiple Electrode Aggregometry: Comparison of Centrifugal and Roller Pumps
Blood trauma may be lower with centrifugal pumps (CPs) than with roller pumps (RPs) during cardiopulmonary bypass (CPB), because, unlike RPs, CPs do not compress the tubing, and shear stress is considered lower in CPs than in RPs. However, relative platelet function remains unclear. Using multiple electrode aggregometry (MEA), we compared platelet function with CP and RP.
Magnitude of Anemia at Discharge Increases 30-Day Hospital Readmissions
Anemia during hospitalization is associated with poor health outcomes
The Use of an Extracorporeal Membrane Oxygenation Anticoagulation Laboratory Protocol Is Associated With Decreased Blood Product Use, Decreased Hemorrhagic Complications, and Increased Circuit Life
We performed a retrospective chart review to determine outcomes for patients placed on extracorporeal membrane oxygenation prior to and after the initiation of our anticoagulation laboratory protocol.
Double Bull’s Eye for Post-Operative Intravenous Iron in Patient Blood Management: Better Outcome and Cost-Effective
The results of this economic evaluation showed that iron-treated patients had a significantly lower allogeneic transfusion rate in comparison to control subjects
Cost of Post-Operative Intravenous Iron Therapy in Total Lower Limb Arthroplasty: A Retrospective, Matched Cohort Study
post-operative intravenous iron after total lower limb arthroplasty seems to be safe and is associated with reduced transfusion rates
Cerebral Oximetry, Neurologic Injury and Blood Conservation, Is There a Connection? (EP Video)
Dr. Michael Brooker discusses a possible connection between cerebral oximetry, neurologic injury and blood management (45:09 minutes).
From Bad to Worse: Anemia on Admission and Hospital-Acquired Anemia
Anemia at hospitalization is often treated as an accompaniment to an underlying illness
A Novel Technique to Retrograde Autologous Prime the Sorin Inspire 6F Dual Chamber Venous Reservoir Oxygenator (EP Video)
Brian Forsberg presents a novel technique for autologous priming the Sorin Inspire 6F Dual oxygenator (14:23 minutes).
A Novel Technique to Retrograde Autologous Prime the Sorin Inspire 6F Dual Chamber Venous Reservoir Oxygenator (EP Video)
Brian Forsberg presents a novel technique for autologous priming the Sorin Inspire 6F Dual oxygenator (14:23 minutes).