Platelet-Rich Plasma Guided Injections: Clinical Application in Peripheral Neuropathies
We have reviewed the literature concerning the clinical application of PRP in peripheral neuropathies and investigated if there is strong evidence to establish the use of PRP in clinical practice as a therapeutic option.
Efficacy and Safety of Autologous Platelet Rich Plasma for the Treatment of Vascular Ulcers in Primary Care: Phase III Study
The objectives of this study are to assess the potential efficacy and safety of autologous platelet rich plasma for the treatment of venous ulcers compared to the conventional treatment (moist wound care) in primary care patients with chronic venous insufficiency (C, clinical class, E, etiology, A, anatomy and P, pathophysiology classification C6).
Blood Glucose Management in the Patient Undergoing Cardiac Surgery: A Review
We discuss our own efforts to improve glycemic management of patients undergoing cardiac surgery at our institution, including keys to success, results of implementation, and patient safety concerns.
Comparison of Three Point-of-Care Testing Devices to Detect Hemostatic Changes in Adult Elective Cardiac Surgery: A Prospective Observational Study
The purpose of this study was to evaluate the ability of the TEG, RoTEM and Sonoclot instruments to detect changes in hemostasis in elective cardiac surgery with cardiopulmonary bypass and to investigate possible correlations between variables from these three instruments and routine hematological coagulation tests.
Application of Veno-Arterial-Venous Extracorporeal Membrane Oxygenation in Differential Hypoxia
Veno-arterial extracorporeal membrane oxygenation (ECMO) through the femoral vein and artery may cause differential hypoxia, i.e., lower PaO2 in the upper body than in the lower body, because of normal cardiac output with severe impairment of pulmonary function.
Very-Short-Term Perioperative Intravenous Iron Administration and Postoperative Outcome in Major Orthopedic Surgery: A Pooled Analysis of Observational Data from 2547 Patients
Despite known limitations of pooled observational analyses, these results suggest that very-short-term perioperative administration of IV iron, with or without rHuEPO, in major lower limb orthopedic procedures is associated with reduced ABT rates and LHS, without increasing postoperative morbidity or mortality.
The Current Place of Aprotinin in the Management of Bleeding
Following its withdrawal in 2007, which is explained in detail in this review, the regulators have now licensed aprotinin for myocardial revascularisation only, which is relatively low-risk for bleeding.
Blood Transfusion Practices in Cardiac Anesthesia
The aim of this review is to provide cardiac surgery specific clinically useful guidelines pertaining to transfusion triggers, optimal haemodilution during CPB, autologous blood transfusion and role of perioperative blood salvage based on available evidence.
Hemorrhage and Thrombosis with Different LVAD Technologies: A Matter of Flow
Much of the morbidity and mortality associated with ventricular assist devices (VADs) is due to haemorrhagic and thrombotic complications.
Evaluation of a Novel Transfusion Algorithm Employing Point-of-care Coagulation Assays in Cardiac Surgery: A Retrospective Cohort Study with Interrupted Time-Series Analysis
This study evaluated a novel transfusion algorithm that uses point-of-care coagulation testing.
Preoperative Continuation of Aspirin Therapy May Improve Perioperative Saphenous Venous Graft Patency After Off-Pump Coronary Artery Bypass Grafting
We sought to evaluate the effect of preoperative continuation of aspirin therapy on perioperative graft patency after OPCAB.
Risk Factors Related to Transfusion Requirements in Patients Undergoing Implantation of Ventricular Assist Devices
This is a retrospective analysis of prospectively collected data between April 2009 and June 2012. Linear regression was used to determine factors associated with increased transfusion.