Anticoagulation Management During Multivessel Coronary Artery Bypass Grafting: A Randomized Trial Comparing Individualized Heparin Management and Conventional Hemostasis Management
Individualized heparin management (IHM) was compared against conventional hemostasis management (CHM) in a randomized, prospective study.
Utilization of Blood Components in Cardiac Surgery: A Single-Centre Retrospective Analysis with Regard to Diagnosis-Related Procedures
Programs of patient blood management (PBM) have been implemented to avoid unnecessary blood transfusions and to standardise the indication of blood transfusions more strictly with aim to improve patients' overall outcomes.
Femoral Veno-Arterial Extracorporeal Life Support with Minimal or No Heparin
Recent technological advances in cardiopulmonary bypass circuits achieving surface bonding with heparin have permitted prolonged extracorporeal life support (ECLS) in experimental studies without the use of systemic anticoagulation.
Improved Long-Term Survival for Diabetic Patients with Surgical Versus Interventional Revascularization
We undertook a prospective registry of coronary revascularization (CR) in diabetic patients with CABG, on-pump and off-pump, and PCI with bare-metal and drug-eluting stents to determine long-term clinical outcomes.
Plasma Free Hemoglobin Is an Independent Predictor of Mortality among Patients on Extracorporeal Membrane Oxygenation Support
Hemolysis is common in all extracorporeal circuits as evident by the elevated plasma free hemoglobin (PFHb) level. We investigated whether increased hemolysis during extracorporeal membrane oxygenation (ECMO) is an independent mortality predictor.
The Efficacy, Safety and Cost-Effectiveness of Intra-Operative Cell Salvage in High-Bleeding-Risk Cardiac Surgery with Cardiopulmonary Bypass: A Prospective Randomized and Controlled Trial
The objective of this study is to evaluate the efficacy, safety and cost-effectiveness of intra-operative cell salvage (CS) in high-bleeding-risk cardiac surgery with cardiopulmonary bypass (CPB).
Effects of Red-Cell Storage Duration on Patients undergoing Cardiac Surgery
The duration of red-cell storage was not associated with significant differences in the change in MODS.
Cardiopulmonary Bypass and Oxidative Stress
Cardiopulmonary bypass (CPB) is associated with the activation of different coagulation, proinflammatory, survival cascades and altered redox state.
Thromboelastometry-Guided Intraoperative Hemostatic Management Reduces Bleeding and Red Cell Transfusion after Pediatric Cardiac Surgery
We tested the hypothesis that the use of a thromboelastometry-guided algorithm for blood product management reduces bloodloss and transfusion requirements.
Activation of Coagulation and Fibrinolysis During Coronary Artery Bypass Grafting: A Comparison Between On-Pump and Off-Pump Techniques
The present study was carried out to compare and document the changes in selected coagulation and fibrinolysis variables in patients undergoing on-pump and off-pump coronary artery bypass grafting.
Activated Coagulation Time Versus Intrinsically Activated Modified Rotational Thromboelastometry in Assessment of Hemostatic Disturbances and Blood Loss after Protamine Administration in Elective Cardiac Surgery
The study aim was to compare the accuracy of hemostatic disorder detection between two point-of-care devices.
Hereditary Antithrombin Deficiency (EP Video)
Barry Fry from Grifols discusses treatment options for Hereditary Antithrombin Deficiency (05:51 minutes).