Role of Bivalirudin for Anticoagulation in Adult Perioperative Cardiothoracic Practice
Bivalirudin, a direct thrombin inhibitor with a fast onset of action and short half-life, is often referred to as an alternative anticoagulant to a heparin/protamine regimen.
Tranexamic Acid and Perioperative Bleeding in Children
Perioperative bleeding and blood product transfusion are associated with significant morbidity and mortality.
Fibrinogen Concentrate as an Alternative to Cryoprecipitate in a Postcardiopulmonary Transfusion Algorithm in Infants Undergoing Cardiac Surgery
Infants undergoing cardiac surgery are at risk for bleeding and massive transfusion due to an immature coagulation system, complex surgeries, and cardiopulmonary bypass (CPB) effects.
Heparin-Free Extracorporeal Life Support Using Tethered Liquid Perfluorocarbon: A Feasibility and Efficacy Study
Coagulation management is the leading challenge during extracorporeal life support (ECLS) due to shear stress and foreign-surface–induced coagulation disturbance during circulation.
Intraoperative Autologous Blood Donation Leads to Fewer Transfusions in Cardiac Surgery
Blood conservation with antifibrinolytics, topical hemostatics, and strict transfusion triggers are becoming commonplace in cardiac surgery.
Impact of Age of Packed RBC Transfusion on Oxygenation in Patients Receiving Extracorporeal Membrane Oxygenation
To determine the effect of age of packed RBCs on tissue oxygenation in children receiving extracorporeal membrane oxygenation support.
Current Evidence and Future Directions of Tranexamic Acid Use, Efficacy, and Dosing for Major Surgical Procedures
Tranexamic acid reduces blood loss and transfusion requirements with no significant thrombotic adverse effects.
Blood Utilization in Revision Versus First-Time Cardiac Surgery: An Update in the Era of Patient Blood Management
Relative to first-time (primary) cardiac surgery, revision cardiac surgery is associated with increased transfusion requirements, but studies comparing these cohorts were performed before patient blood management (PBM) and blood conservation measures were commonplace. The current study was performed as an update to determine if this finding is still evident in the PBM era.
Association Between Anemia and Blood Transfusion With Long-term Mortality After Cardiac Surgery
The aim of this study was to investigate the interactions between preoperative anemia and RBC transfusion and their effect on the long-term survival of patients undergoing cardiac surgery.
BloodSurf 2017: News From the Blood-biomaterial Frontier
From stents and large-diameter vascular grafts, to mechanical heart valves and blood pumps, blood-contacting devices are enjoying significant clinical success owing to the application of systemic antiplatelet and anticoagulation therapies.
The Effect of Various Blood Management Strategies on Intraoperative Red Blood Cell Transfusion in First-time Coronary Artery Bypass Graft Patients
The present study evaluated the distribution of intraoperative interventions in patients undergoing coronary artery bypass graft surgery with cardiopulmonary bypass.
Autologous Platelet-Rich Plasmapheresis in Cardiovascular Surgery: A Narrative Review
Perioperative coagulopathy and bleeding are common complications in cardiovascular surgery with cardiopulmonary bypass and result in an increased rate of allogeneic blood transfusion. Both bleeding and transfusion can increase postoperative mortality and morbidity.