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Pharmacological Prevention of the Deleterious Effects of Cardiopulmonary Bypass
This study was designed to determine if ketoconazole or indomethacin could reduce the adverse effects of extracorporeal circulation.
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Appropriate Clinical Trial Registration Is the Key to Transparent Reporting and Publication
In summary, since the advent of the ClinicalTrials.gov platform, the importance of trial registration has been recognized gradually but consistently throughout the globe. However, challenges remain, including the reluctance to participate on the part of pharmaceutical companies and a mindset among the individual researchers that registration is onerous and may result in the report of insignificant primary outcomes.
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