Comparison of Hemoglobin and Hematocrit Levels at 1, 4 and 24 h after Red Blood Cell Transfusion
The equilibration of Hb and Hct did not differ between one, four and 24 h after a RBC transfusion.
Impact of Intraoperative Cell Salvage on Blood Coagulation Factor Concentrations in Patients Undergoing Cardiac Surgery
Physicians need to consider adequate management of coagulation in patients with major blood loss and the need of large volumes of RBC transfusion.
Bleeding After Cardiac Surgery Is Associated With an Increase in the Total Cost of the Hospital Stay
The impact of a bleeding event on the cost of cardiac surgery is substantial.
Prominent Changes in Blood Coagulation of Patients with SARS-CoV-2 Infection
The coagulation function in patients with SARS-CoV-2 is significantly deranged compared with healthy people, but monitoring D-dimer and FDP values may be helpful for the early identification of severe cases.
Lower Preoperative Hematocrit, Longer Hospital Stay, and Neurocognitive Decline After Cardiac Surgery
A lower preoperative hematocrit and prolonged length of hospital stay are correlated with neurocognitive decline after cardiac surgery utilizing cardiopulmonary bypass.
Are Blood Products Routinely Required in Pediatric Heart Surgery?
The majority of children with a BW > 8.5 kg required no blood products and those with a BW ≤ 8.5 kg required only 1 unit of blood, to prime the cardiopulmonary bypass circuit.
The Impact of Circulation in a Heart–Lung Machine on Function and Survival Characteristics of Red Blood Cells
These changes in key characteristics of the red blood cell aging process likely increase the susceptibility of red blood cells to the various mechanical, osmotic, and immunological stress conditions encountered during and after surgery in the patient’s circulation, and thereby contribute to the side effects of surgery.
Coagulopathy and Antiphospholipid Antibodies in Patients with Covid-19
We describe a patient with Covid-19 and clinically significant coagulopathy, antiphospholipid antibodies, and multiple infarcts. He was one of three patients with these findings in an intensive care unit designated for patients with Covid-19.
Platelet Function Analysed by ROTEM Platelet in Cardiac Surgery after Cardiopulmonary Bypass and Platelet Transfusion
ROTEM platelet with thrombin activation, TRAP‐tem, improved significantly, indicating that platelet transfusion may reverse cardiopulmonary bypass‐induced platelet dysfunction.
Outcome Impact of Different Tranexamic Acid Regimens in Cardiac Surgery with Cardiopulmonary Bypass (OPTIMAL): Rationale, Design, and Study Protocol of a Multicenter Randomized Controlled Trial
The study is designed to identify a TxA dose with maximal efficacy and minimal complications. We hypothesize that the high dose has superior efficacy and noninferior safety to the low dose.
Heparin Dose and Point-of-Care Measurements of Hemostasis in Cardiac Surgery—Results of a Randomized Controlled Trial
Compared with a lower dose of heparin during CPB, a high dose of heparin had little effect on the point-of-care measurements of hemostasis, TEM, and MEA. Based on the similarity of platelet and coagulation activity assessments, the higher heparin dose does not appear to offer benefit during CPB.
The Effect of Restrictive Versus Liberal Transfusion Strategies on Longer-Term Outcomes After Cardiac Surgery: a Systematic Review and Meta-Analysis with Trial Sequential Analysis
In adult patients undergoing cardiac surgery, a restrictive transfusion strategy reduces RBC transfusion without impacting mortality rate or the incidence of other perioperative complications.