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Retrograde Autologous Priming During Cardiopulmonary Bypass Reduces Blood Transfusion Rate in Adult Cardiac Surgery: A Prospective Randomized Clinical Trial
In this experiment, the lowest HCT value during CPB in the study group was significantly higher and only 20% of patients received a blood transfusion. The overall transfusion rate and intraoperative transfusion volume of homologous PRBC units in the RAP group were lower than those in the standard priming group.
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Pulsatility Protects the Endothelial Glycocalyx During Extracorporeal Membrane Oxygenation
The maintenance of the PWSS by pulsatility during ECMO possesses beneficial effects on glycocalyx integrity. Moreover, pulsatility prevents EndMT in endothelial cells, and low pulsatility exhibits the best protective effects. The augmentation of pulsatility may be a plausible future direction to improve the clinical outcome in ECMO.
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