Effect of Ulinastatin on Post-operative Blood Loss and Allogeneic Transfusion in Patients Receiving Cardiac Surgery with Cardiopulmonary Bypass: a Prospective Randomized Controlled Study with 10-year Follow-up
Ulinastatin reduced post-operative blood loss and allogeneic erythrocyte transfusion in heart surgery with CPB. The mortality and major morbidity was comparable among the groups shown by the 10-year follow-up.
Coagulation Ability when Separating from Cardiopulmonary Bypass With and Without Fresh Frozen Plasma: a Pilot Study
Coagulation function 90 min after separating from CPB was not significantly different between the groups. Prior FFP administration before separation did not provide significant improvement in coagulation function.
Does Intraoperative Cell Salvage Reduce Postoperative Infection Rates in Cardiac Surgery?
Cell salvage was directly associated with higher infection rates, but this direct effect was almost completely eliminated by its indirect protective effect through reduced allogeneic blood transfusion.
Intraoperative Plasma Transfusion Volumes and Outcomes in Cardiac Surgery
In patients undergoing cardiac surgery who received intraoperative plasma transfusion, higher plasma transfusion volumes were associated with inferior clinical outcomes.
Hemostatis Analyzer-Supported Hemotherapy Algorithm in Cardiac Surgery: Protocol for a Randomized Controlled Monocentric Trial
Because of the comparability of the Quantra sonorheometry system with the ROTEM measurement methods, the existing hemotherapy treatment algorithm can be adapted to the Quantra device with proof of noninferiority.
Transfusion Use and Hemoglobin Levels by Blood Conservation Method Post Cardiopulmonary Bypass
Although Online-MUF does not appear to reduce blood transfusion, larger prospective randomized controlled studies are required for confirmation.
Multi-Modal Characterization of the Coagulopathy Associated With Extracorporeal Membrane Oxygenation
Therapy protocols for treating extracorporeal membrane oxygenation-associated coagulopathy should be further validated in large-scale prospective clinical investigations.
Clot Formation in Cardiopulmonary Bypass Circuit After Application of Factor XI Concentrate
This case highlights the challenges in the management of patients with FXI deficiency undergoing cardiac surgery and the need for a multidisciplinary approach. Caution is warranted when using FXI concentrate in this patient population.
Are We Able to Dose Protamine Accurately Yet? A Review of the Protamine Conundrum
This review is seeking to capture the current thinking about protamine dosing after cessation of cardiopulmonary bypass.
The Essential Role of Patient Blood Management in a Pandemic: A Call for Action
This multinational and diverse group of authors issue this “Call to Action” underscoring “The Essential Role of Patient Blood Management in the Management of Pandemics” and urging all stakeholders and providers to implement the practical and common-sense principles of PBM and its multi-professional and multimodality approaches.
Patient Blood Management During the COVID‐19 Pandemic ‐ a Narrative Review
This review considers the impact of the COVID‐19 pandemic on the blood supply and specifies important aspects of donor management.
A Narrative Review of Antithrombin Use During Veno-Venous Extracorporeal Membrane Oxygenation in Adults: Rationale, Current Use, Effects on Anticoagulation, and Outcomes
Antithrombin use in veno-venous extracorporeal membrane oxygenation should be investigated on the threshold for supplementation, dose, and time of administration.