Anticoagulation in Neonatal ECMO: An Enigma Despite a Lot of Effort!
This review provides an overview of hemostatic alterations, anticoagulation, monitoring and management, novel anticoagulant use, and circuit modifications for neonatal ECMO. Future considerations are also presented.
Ex Utero Extracorporeal Support as a Model for Fetal Hypoxia and Brain Dysmaturity
This unique model provides opportunities to investigate the pathologic process underlying CHD-associated brain dysmaturity and to evaluate potential fetal neuroprotective therapies.
Venoarterial Extracorporeal Membrane Oxygenation in Sickle Cell Disease for Urgent Cardiac Surgery
This highlights that SCD should not be a counterindication to VA-ECMO, pending multidisciplinary management.
Perioperative Management of Patients With Hereditary Angioedema With Special Considerations for Cardiopulmonary Bypass
The objectives of this review are (1) to review pathophysiology of HAE and laboratory testing, (2) to summarize pertinent pharmacological data on the prophylactic and on-demand treatment strategies, and (3) to discuss available clinical data for perioperative management in cardiovascular surgery.
Methylprednisolone May be Associated with Improved Lung Compliance in Acute Respiratory Distress Syndrome Patients on Veno-Venous Extracorporeal Membrane Oxygenation
Further studies are required to identify appropriate patient selection for methylprednisolone use in patients on veno-venous extracorporeal membrane oxygenation.
Effect of 6% Hydroxyethyl Starch 130/0.4 on Kidney and Haemostatic Function in Cardiac Surgical Patients: a Randomised Controlled Trial
Long‐term mortality and kidney function appeared similar between starch and albumin.
lntraoperative Administration of 6% Hydroxyethyl Starch 130/0.4 is Not Associated with Acute Kidney Injury in Elective Non-Cardiac Surgery: A Sequential and Propensity-Matched Analysis
The intraoperative use of moderate doses of 6% HES 130/0.4 was not associated with increased risk of AKI.
Evaluating The Impact of Pneumonia Prevention Recommendations Following Cardiac Surgery
These pneumonia prevention recommendations may serve as effective targets for avoiding postoperative healthcare-associated infections.
The Use of Neutrophil Lymphocyte Ratio to Predict Complications Post Cardiac Surgery
Higher preoperative and postoperative NLRs are associated with higher rates of complications post cardiac surgery.
Heparin Challenge Test in Patients Undergoing Cardiac Surgery
Our case report indicates that a challenge test may also offer a quick, safe and effective approach in patients with a history of hypersensitivity reactions to heparin with inconclusive diagnostic tests and/or whenever the use of alternative heparins is tricky.
High‐Dose Nitroglycerin Administered During Rewarming Preserves Erythrocyte Deformability in Cardiac Surgery with Cardiopulmonary Bypass
High‐dose nitroglycerin administered during cardiopulmonary bypass improves erythrocyte deformability through activating phosphorylation of aquaporin 1, vasodilator‐stimulated phosphoprotein, and focal adhesion kinase in erythrocytes.