Stromal Cells from the Adipose Tissue-Derived Stromal Vascular Fraction and Culture Expanded AdiposeTissue-Derived Stromal/Stem Cells: A Joint Statement of the International Federation for Adipose Therapeutics (IFATS) and Science and the International So
The goal of this paper is to provide initial guidance for the scientific community working with adipose-derived cells and to facilitate development of international standards based on reproducible parameters.
Mesenchymal Stem Cell Therapy in Osteoarthritis: Advanced Tissue Repair or Intervention with Smouldering Synovial Activation
Desando and co-workers report in Arthritis Research & Therapy that intra-articular delivery of adipose-derived stem cells attenuates progression of synovial activation and joint destruction in osteoarthritis in an experimental rabbit model. Clinical studies are warranted to see whether this approach might be a novel way to combat development of joint destruction in inflammatory subtypes of osteoarthritis.
Adipose-Derived Stem Cells: Fatty Potentials for Therapy
The multi-lineage differentiation capacity, unique immunobiological properties and secretome of Adipose-derived stem cells (ASCs) offer tremendous therapeutic potentials in regenerative medicine.
Long-Term Detection of Human Adipose Derived Mesenchymal Stem Cells After Intra-Articular Injection
These data argue for the feasibility and safety of using intra-articular (IA) delivery of human adipose-derived stem cell (hASC) for the treatment of rheumatic diseases affecting the joints.
Regenerate Augmentation with Bone Marrow Concentrate after Traumatic Bone Loss
The aim of this feasibility study was to investigate the potential of bone marrow aspiration concentrate (BMAC) for percutaneous regenerate augmentation to accelerate bony consolidation of the regenerate.
Establishing proof of concept: Platelet-Rich Plasma and Bone Marrow Aspirate Concentrate may Improve Cartilage Repair Following Surgical Treatment for Osteochondral Lesions of the Talus
The basic science literature therefore establishes the proof of concept that biological adjuncts may improve cartilage repair when used in conjunction with reparative and replacement treatment strategies for osteochondral lesions of the talus.
In Vivo Comparison of the Bone Regeneration Capability of Human Bone Marrow Concentrates vs. Platelet-Rich Plasma
The objective of this study was to evaluate the effects of human BMAC and PRP in combination with β-tricalcium phosphate (β-TCP) on promoting initial bone augmentation in an immunodeficient mouse model.
Platelet-Rich Plasma Application in the Management of Chronic Tendinopathies
Platelets release various cytokines and growth factors which promote angiogenesis, tissue remodeling, and wound healing. We made an extended literature review of the use of PRP in chronic tendinopathies: epicondylitis, rotator cuff, patellar and calcaneal tendinopathies, and plantar fasciitis.
Platelet Rich Plasma use in Allograft ACL Reconstructions: Two-Year Clinical Results of a MOON Cohort Study
The purpose of this study was to evaluate the effect of intra-operative PRP on patient-reported outcomes 2 years after ACL reconstruction with tibialis anterior allograft.
An Exercise-Based Physical Therapy Program for Patients with Patellar Tendinopathy after Platelet-Rich Plasma Injection
This study extensively describes, based on current knowledge, a physical therapy program after PRP injection for patellar tendinopathy patients.
Platelet Rich Plasma. A New Treatment Tool for the Rheumatologist
In the following review we will analyze in detail its principles, preparation, and management regimes. We will reflect on potential adverse effects and, finally, there will be a critical analysis of the scientific evidence that supports its potential use in the rheumatology clinic.
The Positive Effects of Different platelet-Rich Plasma Methods on Human Muscle, Bone, and Tendon Cells
The primary findings of this study suggest the application of different PRP separations may result in a potential beneficial effect on the clinically relevant target cells in vitro.