Intraoperative Red Blood Cell Transfusion During Coronary Artery Bypass Graft Surgery Increases the Risk of Postoperative Low-Output Heart Failure
We examined the relationship between anemia during CPB, RBC transfusion, and risk of low-output heart failure (LOF).
Effect of Alpha-Stat vs. pH-Stat Strategies on Cerebral Oximetry During Moderate Hypothermic Cardiopulmonary Bypass
This study was undertaken to compare the effect of alpha-stat vs. pH-stat strategies for acid-base management on regional cerebral oxygen saturation (RsO2) in patients undergoing moderate hypothermic haemodilution cardiopulmonary bypass (CPB).
Monitoring Activated Clotting Time for Combined Heparin and Aprotinin Application: In Vivo Evaluation of a New Aprotinin-Insensitive Test Using Sonoclot
The aim of our study was to evaluate SaiACT in patients undergoing CPB in presence of heparin and aprotinin.
Leukocyte Filter Enhances Neutrophil Activation during Combined Aortic Valve and Coronary Artery Bypass Surgery
The aim of this prospective, randomized study was to evaluate the impact of continuous leukocyte filtration on the perioperative expression of neutrophil adhesion molecules along with the markers of systemic inflammation during combined coronary artery revascularization and aortic valve surgery due to aortic stenosis.
Platelet-Rich Plasma Stimulates Porcine Articular Chondrocyte Proliferation and Matrix Biosynthesis
The purpose of this study was to examine the effects of PRP on cell proliferation and matrix synthesis by porcine chondrocytes cultured in alginate beads, conditions that promote the retention of the chondrocytic phenotype, in order to determine the plausibility of using this plasma-derived material for engineering cartilage.
Cardiopulmonary Bypass in the Immature Fetus Through Novel Use of a Mini-Centrifugal Pump
The concept that the natural history of certain heart defects could be positively modified through in utero intervention has stimulated extensive research in fetal cardiac intervention and surgery since the early 1980s.
Influence of Hematocrit and Pump Prime on Cerebral Oxygen Saturation in On-Pump Coronary Revascularization
The couplings between cerebral oxygenation (rSO2), on-pump hematocrit and circuit prime are explored in this study.
Changes in Muscle Compartment Pressure After Cardiopulmonary Bypass
Purpose: Hemodilution and inflammation lead to edema and increased muscle compartment pressure after cardiac surgery. The aim of this study was to find whether muscle compartment pressure was affected by the addition of albumin and mannitol to the pump prime, heparin coating or leukocyte depletion. Additionally, we studied the relationship between intraocular pressure and lower leg muscle compartment pressure. Edema during and following cardiac surgery is due to hemodynamic, osmotic and inflammatory changes, according to Starling's Law. We attempted to influence the osmotic balance and reduce the inflammatory response in order to reduce the edema. Methods: Thirty-six patients who underwent cardiac surgery were randomly allocated into four groups. Group A received albumin and mannitol into the pump prime. Group B had an, heparin-coated perfusion system, Group C had a leukocyte-depletion arterial line filter and Group D was the control group, where intraocular pressure was also measured. Results: Lower leg muscle compartment pressure increased significantly during and after cardiac surgery in all groups, but this increase was significantly less in Group A than in the control group 24 h after surgery. No correlation was found between muscular compartment pressure and intraocular pressure. The intraocular pressure profile is different from the muscular compartment pressure and recovers much faster. Conclusion: Lower leg muscle compartment pressure and intraocular pressure behave differently during and after cardiac surgery. Albumin and mannitol added to the pump prime decreases muscle compartment pressure after cardiac surgery.
Direct Evidence of Endothelial Injury During Cardiopulmonary Bypass by Demonstration of Circulating Endothelial Cells
Circulating endothelial cells have recently been established as a novel marker of endothelial damage in a variety of vascular disorders.
The Efficacy of Autologous Platelet Gel in Pain Control and Blood Loss in Total Knee Arthroplasty : An Analysis of the Haemoglobin, Narcotic Requirement and Range of Motion
In this study, 98 unilateral total knee arthroplasties were evaluated retrospectively, 61 of which involved the intaroperative use of platelet gel, and 37 of which served as control subjects.
Is Body Surface Area Still the Best ay to Determine Pump Flow Rate During Cardiopulmonary Bypass?
The aim of this study was to determine which factors, including body surface area, body mass index and lean body mass, best predict SvO2 during CPB.
Long-Term Outcomes of Coronary-Artery Bypass Grafting Versus Stent Implantation
Several studies have compared outcomes for coronary-artery bypass grafting (CABG) and percutaneous coronary intervention (PCI), but most were done before the availability of stenting, which has revolutionized the latter approach.