FDA Never Inspected Chinese Plant Making Baxter’s Heparin
A Chinese manufacturing plant that was never inspected by the U.S. Food and Drug Administration could be the source of a potentially deadly allergic reaction experienced by hundreds of U.S. patients infused with Baxter International Inc.'s blood thinner heparin.
Single-Stage Sinus Augmentation With Cancellous Iliac Bone and Anorganic Bovine Bone in the Presence of Platelet-Rich Plasma in the Miniature Pig
Aim: The aim of the present study was to evaluate the osseointegration of dental implants and bone formation in maxillary sinus grafting with autologous and anorganic bovine bone in the presence of platelet-rich plasma (PRP) in an established animal model. Material and methods: We performed bilateral maxillary sinus augmentation with 50% anorganic bovine bone and simultaneously inserted a titanium screw implant in five minature pigs. Six hundred microlitre autologous PRP were added to the left side (test). The right side (no PRP) served as control. Polychrome sequential labeling was performed. The animals were sacrificed 6 weeks after surgery. Undecalcified ground sections were evaluated by microradiography, digitized histomorphometry and under fluorescent light. Results: The mean bone implant content in the test and control group was 8.4% and 17.3% respectively (P=0.042). The mean height of newly formed mineralized bone in the augmented area of the test group was 3.6 mm and 5.7 mm respectively (P=0.342). In the PRP group, the mean area of newly formed bone in the base of the sinus was enhanced (75.23%) as compared to the control side (51.8%) (P=0.020(*)). Although PRP enhanced bone formation at the base of the maxillary sinus, it neither improved osseointegration of dental implants nor bone in-growth into the bone substitute under the selected experimental conditions.
A Comparison of Activated Coagulation Time-Based Techniques for Anticoagulation During cardiac Surgery With Cardiopulmonary Bypass
This study compared the efficacy of a modified ACT-based system versus an HMS (Hepcon; Medtronic Inc, Minneapolis, MN) for CPB anticoagulation.
Platelet-Rich Fibrin: Evolution of a Second-Generation Platelet Concentrate
This article describes the evolution of this novel platelet concentrate, referred to as PRF.
Datascope CS100 Setup and Operation (Video)
This presentation covers the setup and operation of the Datascope CS100 Intra-Aoric Balloon Pump.
Promoted New Bone Formation in Maxillary Distraction Osteogenesis Using a Tissue-Engineered Osteogenic Material
Bilateral maxillary distraction was performed at a higher rate in rabbits to determine whether locally applied tissue-engineered osteogenic material (TEOM) enhances bone regeneration.
Retrograde Hot-Shot Cardioplegia in Patients With Left Ventricular Hypertrophy Undergoing Aortic Valve Replacement
Background: Intermittent antegrade cold-blood cardioplegia followed by terminal warm-blood cardioplegic reperfusion or hot-shot is reported to reduce myocardial injury in the setting […]
Effect of Pericardial Blood Processing on Postoperative Inflammation and the Complement Pathways
The objective of the present study was to determine the effect of processing of pericardial blood with a cell-saving device (CS) and vacuum-assisted cardiopulmonary bypass (VACPB) on reduction of postoperative inflammation.
A Comparison of Heparin Management Strategies in Infants Undergoing Cardiopulmonary Bypass
In this investigation, we compared a patient-specific heparin concentration-based heparin management protocol with a standard weight-based protocol in infants <6-mo-of-age.
Cell Salvage in Obstetrics (Summary)
Cell salvage in obstetrics has been endorsed by several bodies based on current evidence.
Effect of Perfusion Temperature on the Inflammatory Response During Pediatric Cardiac Surgery
The aim of this prospective study was to compare the inflammatory response in children undergoing CPB for repair of congenital heart defects, randomized to mild or moderate hypothermia.
Antegrade Cerebral Perfusion for Acute Type A Aortic Dissection in 120 Consecutive Patients
The following study investigates clinical results after modification of perfusion technique for cardiopulmonary bypass as well as temperature management.