Reconstituted Fresh Whole Blood Improves Clinical Outcomes Compared With Stored Component Blood Therapy for Neonates Undergoing Cardiopulmonary Bypass for Cardiac Surgery: A Randomized Controlled Trial
This study compared the effects of reconstituted fresh whole blood against standard blood component therapy in neonates undergoing cardiac surgery.
Acid-Base Effects of a Bicarbonate-Balanced Priming Fluid During Cardiopulmonary Bypass: Comparison With Plasma-Lyte 148. A Randomised Single-Blinded Study
In an attempt to prevent this disturbance, we designed a bicarbonate-based crystalloid circuit prime balanced on physico-chemical principles with a strong ion difference of 24 mEq/l and compared its acid-base effects with those of Plasma-Lyte 148, a multiple electrolyte replacement solution containing acetate plus gluconate totalling 50 mEq/l.
The Silent Risks of Blood Transfusion
Rawn discusses some of the newer findings that raise questions about the risks and benefits of blood transfusions.
Blood Conservation Approaches in Surgical Patients
In addition to more restrictive "transfusion triggers", presently available allogeneic blood conservation strategies in surgery include preoperative increase in red blood cells (RBC) mass, techniques or pharmaceutical agents that reduce blood loss, and perioperative blood salvage.
Retrograde Autologous Priming and Allogeneic Blood Transfusions in Adults: A Meta-Analysis
A literature review and meta-analysis were undertaken to assess the clinical effectiveness of retrograde autologous priming of the cardiopulmonary bypass circuit to reduce allogeneic packed red blood transfusions in adult cardiac surgery.
Toward Reducing Perioperative Transfusions
With increased knowledge about the components of blood, transfusions are safer than ever. However, a slight risk of disease transmission still exists along with clerical errors leading to ABO mismatching between donors and recipients.
Platelet-Rich Plasma and Fibrin Glue-Coated Bioactive Ceramics Enhance Growth and Differentiation of Goat Bone Marrow-Derived Stem Cells
New biotechnologies such as tissue engineering require functionally active cells within supportive matrices where the physical and chemical stimulus provided by the matrix is indispensable to determine the cellular behavior.
An Evidence-Based Model Comparing the Cost-effectiveness of Platelet-Rich Plasma Gel to Alternative Therapies for Patients with Nonhealing Diabetic Foot Ulcers
cost-effectiveness analysis compared the potential economic benefit of an autologous, platelet-rich plasma (PRP) gel to alternative therapies in treating nonhealing diabetic foot ulcers.
Role of Platelet-Rich Plasma in Soft Tissue Root-Coverage Procedures: A Review
The aim of this article was to review the current evidence on the role of platelet-rich plasma (PRP) in enhancing root-coverage techniques and discuss the rationale for its use in these applications.
Immunological Complications of Blood Transfusion
In the developed world, most of the reported complications of transfusion have an immunological basis. Although the media and the public are worried about the infectious risks of transfusion, hemovigilance reports show that antigen-antibody reactions are responsible for the vast majority of acute and delayed transfusion reactions
The Systemic Inflammatory Response in Coronary Artery Bypass Grafting: What is the Role of the Very Low Ejection Fraction (EF =/<30%)?
The aim of the present study was to examine the effect of severe left ventricular dysfunction on the activation of systemic inflammatory reaction during and after coronary artery bypass grafting (CABG).