Effects of Haemofiltration and Mannitol Treatment on Cardiopulmonary-Bypass Induced Immunosuppression
The aim of our present study was to evaluate the ability of antioxidant therapy with mannitol or haemofiltration during CPB to modulate this immunosuppression after CPB.
Single Center Experience With a Low Volume Priming Cardiopulmonary Bypass Circuit for Preventing Blood Transfusion in Infants and Small Children
This retrospective study analyzed the current practice of blood transfusion-free open-heart surgery in 536 children weighing 5-20 kg undergoing surgery between 2004 and 2007.
An 11-Year, Single-institution Analysis of Intra-aortic Balloon Pump Use in Cardiac Surgery
The primary objective of this study was to analyze perioperative intra-aortic balloon pump (IABP) insertion in patients undergoing cardiac surgery in the authors' institution from 1995 to 2005 and to propose an explanation for changes in use over this period.
Root Coverage Using Acellular Dermal Matrix and Comparing a Aoronally Positioned Tunnel With and Without Platelet-Rich Plasma: A Pilot Study in Humans
The primary aim of this randomized, controlled, blinded clinical pilot study was to compare the percentage of recession defect coverage obtained with a coronally positioned tunnel (CPT) plus an acellular dermal matrix allograft (ADM) to that of a CPT plus ADM and platelet-rich plasma (CPT/PRP) 4 months post-surgically.
Thrombelastography
In the past decades there has been an increasing interest for TEG in clinical practice. In this paper we present the rationale for the method and a discussion of the possible application of TEG.
Integrated Model of Endothelial NO Regulation and Systemic Circulation for the Comparison Between Pulsatile and Continuous Perfusion
Many experimental studies concerning nitric oxide (NO) release from endothelium and its vasodilative action are available in the literature, but no analytical description or modeling of these phenomena can be found.
Pediatric Off-label Use of Recombinant Factor VIIa
Our goal was to report our institutional experience with recombinant factor VIIa for the treatment and/or prevention of bleeding in nonhemophiliac children.
Transfusion-Related Acute Lung Injury: Current Concepts for the Clinician
Much more research is needed to understand the blood component and patient risk factors for TRALI so that novel strategies for treatment and additional measures to reduce the risk of TRALI can be developed.
Fibroblastic Response to Treatment With Different Preparations Rich in Growth Factors
Preparations rich in growth factors (PRGF) release them plus bioactive proteins at localized sites, with the aim of triggering healing and regenerative processes.
Body Perfusion During Adult Cardiopulmonary Bypass is Improved by Pulsatile Flow With Intra-Aortic Balloon Pump
To evaluate if the use of an intra-aortic balloon pump (IABP) during cardioplegic arrest improves body perfusion.
Tranexamic Acid and Aprotinin in Low and Intermediate-Risk Cardiac Surgery: A Non-Sponsored, Double-Blind, Randomised, Placebo-Controlled Trial
We wanted to compare the effectiveness of tranexamic acid versus aprotinin in reducing postoperative blood loss and transfusion requirements in the patient group representing the majority of cardiac surgery patients: low- and intermediate-risk patients.
Reduction in Clinical Varaibility by Attention to Detail, Self Reflection & A Little Mathematics (Video)
Al Stammers presents his experiences at Geisinger Medical Center on reducing clinical varability through a multifocal approach.